Effect of oral contraceptive use on weight loss and body composition following low-calorie diet intervention.
Body composition
Fat-mass
Low-calorie diet
Oral contraceptives
Weight loss
Journal
Clinical nutrition ESPEN
ISSN: 2405-4577
Titre abrégé: Clin Nutr ESPEN
Pays: England
ID NLM: 101654592
Informations de publication
Date de publication:
04 2022
04 2022
Historique:
received:
22
03
2021
revised:
01
02
2022
accepted:
08
02
2022
entrez:
25
3
2022
pubmed:
26
3
2022
medline:
31
3
2022
Statut:
ppublish
Résumé
Energy restriction promoted by hypocaloric diets is one of the most studied interventions to achieve weight loss. However, there are many factors which may influence the weight loss process. Hormonal contraception is an important factor to be investigated. To evaluate the effect of oral contraceptive use on weight loss following 500-kcal reduction diet intervention for 1-month. We conducted a single-blind controlled study in which 19 healthy women aged 18-25 years were divided into oral contraceptive use group (COC, n = 9) or no hormonal contraception use group (NHC, n = 10). Anthropometric measurements were assessed at baseline and after 4 weeks of intervention. Both COC and NHC groups achieved significant body weight, body fat, and lean body mass loss following 4 weeks of caloric restriction diet intervention. COC group lost more weight (2.87 kg) than NHC group (1.36 kg) (p < 0.001). In a month's time, daily reduction of 500-kcal resulted in reduction of body weight and body fat. COC group lost more weight than NHC group. Given the limitations of the study, these data should be interpreted with caution. More studies are necessary to verify the effects of oral contraceptive use on weight loss.
Sections du résumé
BACKGROUND
Energy restriction promoted by hypocaloric diets is one of the most studied interventions to achieve weight loss. However, there are many factors which may influence the weight loss process. Hormonal contraception is an important factor to be investigated.
PURPOSE
To evaluate the effect of oral contraceptive use on weight loss following 500-kcal reduction diet intervention for 1-month.
METHODS
We conducted a single-blind controlled study in which 19 healthy women aged 18-25 years were divided into oral contraceptive use group (COC, n = 9) or no hormonal contraception use group (NHC, n = 10). Anthropometric measurements were assessed at baseline and after 4 weeks of intervention.
RESULTS
Both COC and NHC groups achieved significant body weight, body fat, and lean body mass loss following 4 weeks of caloric restriction diet intervention. COC group lost more weight (2.87 kg) than NHC group (1.36 kg) (p < 0.001).
CONCLUSION
In a month's time, daily reduction of 500-kcal resulted in reduction of body weight and body fat. COC group lost more weight than NHC group. Given the limitations of the study, these data should be interpreted with caution. More studies are necessary to verify the effects of oral contraceptive use on weight loss.
Identifiants
pubmed: 35331498
pii: S2405-4577(22)00055-9
doi: 10.1016/j.clnesp.2022.02.006
pii:
doi:
Substances chimiques
Contraceptives, Oral
0
Types de publication
Controlled Clinical Trial
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
247-252Informations de copyright
Copyright © 2022 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare having no conflict of interest.