Calorie restriction changes the anxiety-like behaviour of ageing male Wistar rats in an onset- and duration-dependent manner.
Ageing
Anxiety
Behaviour
Calorie restriction
Dopamine receptors
Journal
Mechanisms of ageing and development
ISSN: 1872-6216
Titre abrégé: Mech Ageing Dev
Pays: Ireland
ID NLM: 0347227
Informations de publication
Date de publication:
06 2022
06 2022
Historique:
received:
17
11
2021
revised:
16
03
2022
accepted:
17
03
2022
pubmed:
26
3
2022
medline:
14
5
2022
entrez:
25
3
2022
Statut:
ppublish
Résumé
Although initially recognized as a universally beneficial approach for the prevention of age-related impairments, the outcome of calorie restriction (CR) is now known to depend on several factors, most notably the age of the subject at the CR commencement, and CR duration. We aimed to examine if and how CR affects anxiety-like behaviour when it is introduced at middle age and late middle age. In addition, as the dopaminergic system is one of the main neurotransmitter systems involved in controlling anxiety, we examined the expression of dopamine receptors (D
Identifiants
pubmed: 35331743
pii: S0047-6374(22)00048-3
doi: 10.1016/j.mad.2022.111666
pii:
doi:
Substances chimiques
Receptors, Dopamine
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
111666Informations de copyright
Copyright © 2022. Published by Elsevier B.V.