Viscoelastic Particle Focusing and Separation in a Spiral Channel.
inertial focusing
particle separation
spiral channel
viscoelastic flow
Journal
Micromachines
ISSN: 2072-666X
Titre abrégé: Micromachines (Basel)
Pays: Switzerland
ID NLM: 101640903
Informations de publication
Date de publication:
25 Feb 2022
25 Feb 2022
Historique:
received:
01
02
2022
revised:
18
02
2022
accepted:
22
02
2022
entrez:
26
3
2022
pubmed:
27
3
2022
medline:
27
3
2022
Statut:
epublish
Résumé
As one type of non-Newtonian fluid, viscoelastic fluids exhibit unique properties that contribute to particle lateral migration in confined microfluidic channels, leading to opportunities for particle manipulation and separation. In this paper, particle focusing in viscoelastic flow is studied in a wide range of polyethylene glycol (PEO) concentrations in aqueous solutions. Polystyrene beads with diameters from 3 to 20 μm are tested, and the variation of particle focusing position is explained by the coeffects of inertial flow, viscoelastic flow, and Dean flow. We showed that particle focusing position can be predicted by analyzing the force balance in the microchannel, and that particle separation resolution can be improved in viscoelastic flows.
Identifiants
pubmed: 35334653
pii: mi13030361
doi: 10.3390/mi13030361
pmc: PMC8954746
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : NICHD NIH HHS
ID : R44 HD095355
Pays : United States
Organisme : NIH HHS
ID : 5R44HD095355-03
Pays : United States
Organisme : Office of Science
ID : DE-SC0019285
Références
J Appl Phys. 2021 Jul 21;130(3):034902
pubmed: 34334807
Appl Phys Lett. 2019 Dec 23;115(26):263702
pubmed: 32127720
Sci Rep. 2013 Nov 19;3:3258
pubmed: 24247252
Anal Chem. 2016 Dec 20;88(24):12303-12309
pubmed: 28193020
Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):18892-7
pubmed: 18025477
Anal Chem. 2009 Oct 15;81(20):8459-65
pubmed: 19761190
Transl Androl Urol. 2018 Jul;7(Suppl 3):S336-S347
pubmed: 30159240
Lab Chip. 2012 Nov 7;12(21):4228-31
pubmed: 22992833
Lab Chip. 2014 Aug 7;14(15):2739-61
pubmed: 24914632
Anal Chem. 2018 Nov 6;90(21):12783-12790
pubmed: 30346136
Lab Chip. 2009 Nov 7;9(21):3038-46
pubmed: 19823716
Micromachines (Basel). 2021 Oct 18;12(10):
pubmed: 34683316
Small. 2013 Mar 11;9(5):685-90
pubmed: 23143944
Lab Chip. 2016 Mar 21;16(6):992-1001
pubmed: 26853995
Electrophoresis. 2002 Jul;23(13):1973-83
pubmed: 12210248
Lab Chip. 2009 Oct 21;9(20):2973-80
pubmed: 19789752
Annu Rev Biomed Eng. 2014 Jul 11;16:371-96
pubmed: 24905880
Anal Chem. 2008 Mar 1;80(5):1641-8
pubmed: 18220368
Micromachines (Basel). 2019 Sep 10;10(9):
pubmed: 31510006
Med Biol Eng Comput. 2010 Oct;48(10):999-1014
pubmed: 20414811
Electrophoresis. 2014 Mar;35(5):691-713
pubmed: 24338825
Lab Chip. 2008 Nov;8(11):1906-14
pubmed: 18941692
Microsyst Nanoeng. 2020 Dec 14;6:113
pubmed: 34567720
Lab Chip. 2007 Dec;7(12):1644-59
pubmed: 18030382
Lab Chip. 2013 Mar 21;13(6):1121-32
pubmed: 23353899
Biomicrofluidics. 2021 Jul 02;15(4):041501
pubmed: 34262632
Analyst. 2021 May 21;146(10):3368-3377
pubmed: 33871507
Rev Sci Instrum. 2004 Sep;75(9):2787-809
pubmed: 16878180
Sci Rep. 2020 Dec 7;10(1):21385
pubmed: 33288839
Phys Rev Lett. 2007 Jun 8;98(23):234501
pubmed: 17677908
Nature. 2006 Jul 27;442(7101):368-73
pubmed: 16871203
Nat Commun. 2014 Jun 18;5:4120
pubmed: 24939508
Lab Chip. 2021 Sep 28;21(19):3762-3774
pubmed: 34581374
Micromachines (Basel). 2021 Mar 03;12(3):
pubmed: 33802356