Randomized controlled trial of all-inside and standard single-bundle anterior cruciate ligament reconstruction with functional, MRI-based graft maturity and patient-reported outcome measures.


Journal

BMC musculoskeletal disorders
ISSN: 1471-2474
Titre abrégé: BMC Musculoskelet Disord
Pays: England
ID NLM: 100968565

Informations de publication

Date de publication:
26 Mar 2022
Historique:
received: 18 10 2021
accepted: 16 03 2022
entrez: 26 3 2022
pubmed: 27 3 2022
medline: 31 3 2022
Statut: epublish

Résumé

All-inside anterior cruciate ligament reconstruction (ACLR) is a novel technique that has gained attention due to its minimally invasive and graft-saving properties. However, studies comparing MRI-based graft maturity between all-inside and standard ACLR are lacking. This study focused on the functional, knee laxity, and MRI-based graft maturity characteristics of all-inside and standard single-bundle ACLR. Randomized controlled trial (RCT). Fifty-four patients were randomly assigned to an all-inside reconstruction group (n = 27) or standard reconstruction group (n = 27). Using the same rehabilitation strategy. The Tegner, International Knee Documentation Committee, and Lysholm scores were recorded at postoperative months 3, 6, and 12 to assess functional recovery. MRI was conducted to measure the signal/noise quotient (SNQ) of the intra-articular graft to assess the maturity. A higher SNQ indicates lower graft maturity. Knee laxity was assessed using GNRB arthrometer at the postoperative month 12. The graft SNQ of the all-inside group was significantly higher than that of the standard group at postoperative month 6 (p < 0.05). There was no statistical difference in graft SNQ between the two groups at postoperative months 3 and 12 (p > 0.05). Both groups exhibited the highest SNQ in the middle region of the graft, followed by the proximal region, and the distal region. Functional scores improved significantly for both groups and had no statistical difference (p > 0.05). The knee laxity was higher in the all-inside group (p < 0.05) at postoperative month 12. There was no correlation between the functional scores and graft maturity in both groups (p > 0.05). All-inside and standard single-bundle ACLR show good functional outcomes; however, knee laxity was relatively higher in the all-inside ACLR group than in the standard ACLR group. Moreover, both techniques exhibited poor maturity in the middle graft region and the best in the distal region. Graft maturity with all-inside ACLR is inferior to that with standard ACLR in the early postoperative stages. There is no correlation between knee function and graft maturity. Clinical trial registration numbers: ChiCTR1800018543 . Date of registration: 09/23/2018.

Sections du résumé

BACKGROUND BACKGROUND
All-inside anterior cruciate ligament reconstruction (ACLR) is a novel technique that has gained attention due to its minimally invasive and graft-saving properties. However, studies comparing MRI-based graft maturity between all-inside and standard ACLR are lacking.
PURPOSE OBJECTIVE
This study focused on the functional, knee laxity, and MRI-based graft maturity characteristics of all-inside and standard single-bundle ACLR.
STUDY DESIGN METHODS
Randomized controlled trial (RCT).
METHODS METHODS
Fifty-four patients were randomly assigned to an all-inside reconstruction group (n = 27) or standard reconstruction group (n = 27). Using the same rehabilitation strategy. The Tegner, International Knee Documentation Committee, and Lysholm scores were recorded at postoperative months 3, 6, and 12 to assess functional recovery. MRI was conducted to measure the signal/noise quotient (SNQ) of the intra-articular graft to assess the maturity. A higher SNQ indicates lower graft maturity. Knee laxity was assessed using GNRB arthrometer at the postoperative month 12.
RESULTS RESULTS
The graft SNQ of the all-inside group was significantly higher than that of the standard group at postoperative month 6 (p < 0.05). There was no statistical difference in graft SNQ between the two groups at postoperative months 3 and 12 (p > 0.05). Both groups exhibited the highest SNQ in the middle region of the graft, followed by the proximal region, and the distal region. Functional scores improved significantly for both groups and had no statistical difference (p > 0.05). The knee laxity was higher in the all-inside group (p < 0.05) at postoperative month 12. There was no correlation between the functional scores and graft maturity in both groups (p > 0.05).
CONCLUSIONS CONCLUSIONS
All-inside and standard single-bundle ACLR show good functional outcomes; however, knee laxity was relatively higher in the all-inside ACLR group than in the standard ACLR group. Moreover, both techniques exhibited poor maturity in the middle graft region and the best in the distal region. Graft maturity with all-inside ACLR is inferior to that with standard ACLR in the early postoperative stages. There is no correlation between knee function and graft maturity.
TRIAL REGISTRATION BACKGROUND
Clinical trial registration numbers: ChiCTR1800018543 . Date of registration: 09/23/2018.

Identifiants

pubmed: 35337306
doi: 10.1186/s12891-022-05231-x
pii: 10.1186/s12891-022-05231-x
pmc: PMC8957124
doi:

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Pagination

289

Subventions

Organisme : Shenzhen Health and Family Planning Commission
ID : SZLY2017004
Organisme : Shenzhen Health and Family Planning Commission
ID : SZLY2017004
Organisme : Shenzhen Health and Family Planning Commission
ID : SZLY2017004
Organisme : Shenzhen Health and Family Planning Commission
ID : SZLY2017004
Organisme : Shenzhen Health and Family Planning Commission
ID : SZLY2017004
Organisme : Shenzhen Health and Family Planning Commission
ID : SZLY2017004
Organisme : Shenzhen Health and Family Planning Commission
ID : SZLY2017004
Organisme : Shenzhen Health and Family Planning Commission
ID : SZLY2017004
Organisme : Shenzhen Health and Family Planning Commission
ID : SZLY2017004

Informations de copyright

© 2022. The Author(s).

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Auteurs

Rubing Lin (R)

Peking University Shenzhen Hospital, Clinical College of Anhui Medical University, Lianhua Road 1120, Futian District, Shenzhen City, Guangdong Province, 518036, People's Republic of China.
Peking University Shenzhen Hospital, Lianhua Road 1120, FuTian District, ShenZhen City, GuangDong Province, 518036, People's Republic of China.

Qiuwen Zhong (Q)

Peking University Shenzhen Hospital, Lianhua Road 1120, FuTian District, ShenZhen City, GuangDong Province, 518036, People's Republic of China.

Xiao Wu (X)

Peking University Shenzhen Hospital, Lianhua Road 1120, FuTian District, ShenZhen City, GuangDong Province, 518036, People's Republic of China.

Lei Cui (L)

Peking University Shenzhen Hospital, Clinical College of Anhui Medical University, Lianhua Road 1120, Futian District, Shenzhen City, Guangdong Province, 518036, People's Republic of China.
Peking University Shenzhen Hospital, Lianhua Road 1120, FuTian District, ShenZhen City, GuangDong Province, 518036, People's Republic of China.

Rong Huang (R)

Peking University Shenzhen Hospital, Lianhua Road 1120, FuTian District, ShenZhen City, GuangDong Province, 518036, People's Republic of China.

Qianhua Deng (Q)

Peking University Shenzhen Hospital, Lianhua Road 1120, FuTian District, ShenZhen City, GuangDong Province, 518036, People's Republic of China.

Jianwei Zuo (J)

Peking University Shenzhen Hospital, Lianhua Road 1120, FuTian District, ShenZhen City, GuangDong Province, 518036, People's Republic of China.

Changqing Jiang (C)

Huazhong University of Science and Technology Union Shenzhen Hospital, Taoyuan Road 89, Nanshan District, Shenzhen City, GuangDong Province, 518036, People's Republic of China.

Wei Li (W)

Peking University Shenzhen Hospital, Lianhua Road 1120, FuTian District, ShenZhen City, GuangDong Province, 518036, People's Republic of China. lwjnu2003@126.com.

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