Mechanical power thresholds during mechanical ventilation: An experimental study.

Animals Lung / pathology Respiration, Artificial / adverse effects Respiratory Function Tests Respiratory Rate Swine Ventilator-Induced Lung Injury
mechanical power mechanical ventilation treshold ventilation induced lung injury

Journal

Physiological reports
ISSN: 2051-817X
Titre abrégé: Physiol Rep
Pays: United States
ID NLM: 101607800

Informations de publication

Date de publication:
03 2022
Historique:
received: 16 02 2022
accepted: 22 02 2022
entrez: 27 3 2022
pubmed: 28 3 2022
medline: 5 4 2022
Statut: ppublish

Résumé

The extent of ventilator-induced lung injury may be related to the intensity of mechanical ventilation--expressed as mechanical power. In the present study, we investigated whether there is a safe threshold, below which lung damage is absent. Three groups of six healthy pigs (29.5 ± 2.5 kg) were ventilated prone for 48 h at mechanical power of 3, 7, or 12 J/min. Strain never exceeded 1.0. PEEP was set at 4 cmH

Identifiants

DOI: 10.14814/phy2.15225 PMID: 35340133 PMC: PMC8957661
pubmed: 35340133
doi: 10.14814/phy2.15225
pmc: PMC8957661
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e15225

Informations de copyright

© 2022 The Authors. Physiological Reports published by Wiley Periodicals LLC on behalf of The Physiological Society and the American Physiological Society.

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Auteurs

Federica Romitti (F)

Department of Anesthesiology, University Medical Center Göttingen, Göttingen, Germany.

Mattia Busana (M)

Department of Anesthesiology, University Medical Center Göttingen, Göttingen, Germany.
ORCID: 0000-0002-1626-1278

Maria Michela Palumbo (MM)

Department of Anesthesiology, University Medical Center Göttingen, Göttingen, Germany.

Matteo Bonifazi (M)

Department of Anesthesiology, University Medical Center Göttingen, Göttingen, Germany.

Lorenzo Giosa (L)

Department of Anesthesiology, University Medical Center Göttingen, Göttingen, Germany.

Francesco Vassalli (F)

Department of Anesthesiology, University Medical Center Göttingen, Göttingen, Germany.

Alessandro Gatta (A)

Department of Anesthesia and Intensive Care, "Ceccarini"Hospital, AUSL della Romagna, Riccione, Italy.

Francesca Collino (F)

Department of Anesthesia, Intensive Care and Emergency, "Citta' della Salute e della Scienza" Hospital, Turin, Italy.

Irene Steinberg (I)

Department of Anesthesiology, University Medical Center Göttingen, Göttingen, Germany.

Simone Gattarello (S)

Department of Anesthesiology, University Medical Center Göttingen, Göttingen, Germany.

Stefano Lazzari (S)

Department of Anesthesiology, University Medical Center Göttingen, Göttingen, Germany.

Paola Palermo (P)

Department of Anesthesiology, University Medical Center Göttingen, Göttingen, Germany.

Ahmed Nasr (A)

Department of Pathology, Papa Giovanni XXIII Hospital, Bergamo, Italy.

Ann-Kathrin Gersmann (AK)

Institute of Pathology, University Medical Center Göttingen, University of Göttingen, Germany.

Annika Richter (A)

Institute of Pathology, University Medical Center Göttingen, University of Göttingen, Germany.

Peter Herrmann (P)

Department of Anesthesiology, University Medical Center Göttingen, Göttingen, Germany.

Onnen Moerer (O)

Department of Anesthesiology, University Medical Center Göttingen, Göttingen, Germany.

Leif Saager (L)

Department of Anesthesiology, University Medical Center Göttingen, Göttingen, Germany.
Outcomes Research Consortium, Cleveland, Ohio, USA.
ORCID: 0000-0003-3416-4727

Luigi Camporota (L)

Department of Adult Critical Care, Guy's and St Thomas' NHS Foundation Trust, Health Centre for Human and Applied Physiological Sciences, London, United Kingdom.

John J Marini (JJ)

Department of Pulmonary and Critical Care Medicine, University of Minnesota and Regions Hospital, St. Paul, Minnesota, USA.

Michael Quintel (M)

Department of Anesthesiology, University Medical Center Göttingen, Göttingen, Germany.

Konrad Meissner (K)

Department of Anesthesiology, University Medical Center Göttingen, Göttingen, Germany.

Luciano Gattinoni (L)

Department of Anesthesiology, University Medical Center Göttingen, Göttingen, Germany.
ORCID: 0000-0001-5380-2494

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Classifications MeSH

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questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic respiratoire › Tests de la fonction respiratoire › Mechanical power thresholds during mechanical...
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