Biological effects of olive oil phenolic compounds on mitochondria.
Antioxidants
Mediterranean diet
cell death
hydroxytyrosol
mitophagy
oleuropein
Journal
Molecular & cellular oncology
ISSN: 2372-3556
Titre abrégé: Mol Cell Oncol
Pays: United States
ID NLM: 101642411
Informations de publication
Date de publication:
2022
2022
Historique:
entrez:
28
3
2022
pubmed:
29
3
2022
medline:
29
3
2022
Statut:
epublish
Résumé
Phenolic compounds derived from olive oil have beneficial health properties against cancer, neurodegenerative, and metabolic diseases. Therefore, there are discrepancies in their impact on mitochondrial function that result in changes in oxidative capacity, mitochondrial respiration, and energetic demands. This review focuses on the versatile role of oleuropein, a potent antioxidant that regulates the AMPK/SIRT1/mTOR pathway to modulate autophagy/mitophagy and maintain metabolic homeostasis.
Identifiants
pubmed: 35340790
doi: 10.1080/23723556.2022.2044263
pii: 2044263
pmc: PMC8942445
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
2044263Informations de copyright
© 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.
Déclaration de conflit d'intérêts
No potential conflict of interest was reported by the authors.
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