Impacted gutkha presenting as an intrabronchial mass lesion leading to post-obstructive pneumonia.

Aspiration Betel nut CMA, chronic micro aspiration CT CT, computed tomography DNA, deoxyribonucleic acid Endobronchial mass Gutkha Pneumonia

Journal

Respiratory medicine case reports
ISSN: 2213-0071
Titre abrégé: Respir Med Case Rep
Pays: England
ID NLM: 101604463

Informations de publication

Date de publication:
2022
Historique:
received: 04 11 2021
revised: 03 02 2022
accepted: 17 02 2022
entrez: 28 3 2022
pubmed: 29 3 2022
medline: 29 3 2022
Statut: epublish

Résumé

A 66-year-old man presented with a chief complaint of difficulty breathing and productive cough. CT scan of the chest revealed an endobronchial mass with associated "tree-in-bud" opacities. A bronchoscopic biopsy of the mass was performed due to clinical suspicion of malignancy. Microscopic examination revealed inflamed endobronchial mucosa, granulation tissue and abundant fragments of uncharacterized organic material, compatible with aspiration. Detailed history revealed a history of chewing "gutkha", a form of smokeless tobacco comprising a mixture of betel nut and other condiments. Microscopic sections of a betel nut and the "gutkha mix" processed subsequently in the histology laboratory were found to be similar to the organic material found in the mass. Thus, a diagnosis of impacted betel nut mixture leading to post-obstructive pneumonia was rendered.

Identifiants

pubmed: 35342705
doi: 10.1016/j.rmcr.2022.101616
pii: S2213-0071(22)00038-7
pmc: PMC8941267
doi:

Types de publication

Case Reports

Langues

eng

Pagination

101616

Informations de copyright

© 2022 Published by Elsevier Ltd.

Déclaration de conflit d'intérêts

The authors whose names are listed below certify that they have NO affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.

Références

IARC Monogr Eval Carcinog Risks Hum. 2004;85:1-334
pubmed: 15635762
Addict Health. 2018 Jan;10(1):52-63
pubmed: 30627385
Am J Surg Pathol. 2007 May;31(5):752-9
pubmed: 17460460
Int J Pediatr Otorhinolaryngol. 2013 Oct;77(10):1683-8
pubmed: 23962764
J Thorac Dis. 2017 Sep;9(9):3398-3409
pubmed: 29221325
Ann Acad Med Singap. 2004 Jul;33(4 Suppl):31-6
pubmed: 15389304
Carcinogenesis. 1985 Feb;6(2):295-303
pubmed: 3971493
Respir Care. 2015 Oct;60(10):1438-48
pubmed: 25969517
J Oral Pathol Med. 1994 Feb;23(2):65-9
pubmed: 8164155

Auteurs

Swati Bhardwaj (S)

Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai Hospital, New York, NY, USA.

Paul A Chung (PA)

Department of Pulmonary Medicine and Critical Care, Northwestern University Medical Center, Chicago, IL, USA.

Recep Nigdelioglu (R)

Department of Pathology and Laboratory Medicine, Loyola University Medical Center, Maywood, IL, USA.

Michal Reid (M)

Department of Pulmonary Medicine and Critical Care, Loyola University Medical Center, Maywood, IL, USA.

Monica Lockhart (M)

Department of Pathology and Laboratory Medicine, Loyola University Medical Center, Maywood, IL, USA.

Sean M Forsythe (SM)

Department of Pulmonary Medicine and Critical Care, Loyola University Medical Center, Maywood, IL, USA.

Vijayalakshmi Ananthanarayanan (V)

Department of Pathology and Laboratory Medicine, Loyola University Medical Center, Maywood, IL, USA.

Classifications MeSH