A New Look at Codon Usage and Protein Expression.


Journal

EPiC series in computing
ISSN: 2398-7340
Titre abrégé: Epic Ser Comput
Pays: England
ID NLM: 9918231297406676

Informations de publication

Date de publication:
2019
Historique:
entrez: 28 3 2022
pubmed: 1 1 2019
medline: 1 1 2019
Statut: ppublish

Résumé

%MinMax, a model of intra-gene translational elongation rate, relies on codon usage frequencies. Historically, %MinMax has used tables that measure codon usage bias for all genes in an organism, such as those found at HIVE-CUT. In this paper, we provide evidence that codon usage bias based on all genes is insufficient to accurately measure absolute translation rate. We show that alternative "High-

Identifiants

pubmed: 35342824
doi: 10.29007/d4tz
pmc: PMC8953497
mid: NIHMS1728045
doi:

Types de publication

Journal Article

Langues

eng

Pagination

104-112

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM120733
Pays : United States

Références

BMC Bioinformatics. 2017 Sep 2;18(1):391
pubmed: 28865429
Annu Rev Biophys. 2015;44:143-66
pubmed: 25747594
Mol Cell. 2016 Feb 4;61(3):341-351
pubmed: 26849192
Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):11434-11439
pubmed: 29073068
Nucleic Acids Res. 1987 Feb 11;15(3):1281-95
pubmed: 3547335
Biochim Biophys Acta Biomembr. 2018 Dec;1860(12):2479-2485
pubmed: 30279149
PLoS Genet. 2014 Jun 05;10(6):e1004392
pubmed: 24901308
PLoS One. 2008;3(10):e3412
pubmed: 18923675
Nat Biotechnol. 2016 Jan;34(1):104-10
pubmed: 26641532
FEBS Lett. 1999 Dec 3;462(3):387-91
pubmed: 10622731
Protein Sci. 2018 Jan;27(1):356-362
pubmed: 29090506
J Mol Biol. 2012 Sep 21;422(3):328-35
pubmed: 22705285
FEBS Lett. 2018 May;592(9):1554-1564
pubmed: 29624661
PLoS Comput Biol. 2017 May 5;13(5):e1005531
pubmed: 28475588
Trends Cell Biol. 2001 Jul;11(7):294-7
pubmed: 11413040
Nature. 2003 Oct 16;425(6959):737-41
pubmed: 14562106
Nat Struct Mol Biol. 2013 Feb;20(2):237-43
pubmed: 23262490
Genome Biol Evol. 2015 May 14;7(6):1559-79
pubmed: 25977456
Nat Struct Mol Biol. 2009 Mar;16(3):274-80
pubmed: 19198590
J Am Chem Soc. 2014 Jan 22;136(3):858-61
pubmed: 24392935
Cell. 2010 Apr 16;141(2):344-54
pubmed: 20403328
Bioinformatics. 2018 Jul 15;34(14):2496-2498
pubmed: 29522124

Auteurs

Gabriel Wright (G)

Department of Computer Science, University of Notre Dame.

Anabel Rodriguez (A)

Department of Chemistry & Biochemistry, University of Notre Dame.

Patricia L Clark (PL)

Department of Chemistry & Biochemistry, University of Notre Dame.

Scott Emrich (S)

Department of Electrical Engineering & Computer Science, University of Tennessee, Knoxville.

Classifications MeSH