Bilateral antererior circulation stroke: A rare but threatening consequence of pituitary apoplexy. Case report and systematic literature review.


Journal

The neuroradiology journal
ISSN: 2385-1996
Titre abrégé: Neuroradiol J
Pays: United States
ID NLM: 101295103

Informations de publication

Date de publication:
Dec 2023
Historique:
medline: 15 11 2023
pubmed: 29 3 2022
entrez: 28 3 2022
Statut: ppublish

Résumé

Brain stroke is a rare, life-threatening condition associated with pituitary apoplexy (PA), resulting from direct arterial occlusion due to mechanical compression secondary to the sudden enlargement of the pituitary adenoma, or to vessel vasospasm, induced by tumor hemorrhage. We report the case of a 64-year-old woman with PA complicated by bilateral anterior circulation stroke due to critical stenosis of both anterior cerebral arteries (ACA). Despite the quick surgical decompression and consequent blood flow restoration, the neurological conditions of the patient did not improve and she died 18 days later. Ten other cases of anterior circulation stroke due to PA were retrieved in a systematic review of literature. Clinical and neuroradiological features of these patients and treatment outcome were assessed to suggest the most proper management. The onset of neurological symptoms suggestive for brain stroke in patients with PA requires performing an emergency Magnetic Resonance Imaging (MRI), including Diffusion-weighted and angiographic MR-sequences. The role of surgery in these cases is debated, however, transsphenoidal adenomectomy would permit us to decompress the ACA and restore blood flow in their territories. Although the prognosis of PA-induced anterior circulation stroke is generally poor, a timely diagnosis and treatment would be paramount for improving patient outcome.

Sections du résumé

BACKGROUND BACKGROUND
Brain stroke is a rare, life-threatening condition associated with pituitary apoplexy (PA), resulting from direct arterial occlusion due to mechanical compression secondary to the sudden enlargement of the pituitary adenoma, or to vessel vasospasm, induced by tumor hemorrhage.
CASE REPORT METHODS
We report the case of a 64-year-old woman with PA complicated by bilateral anterior circulation stroke due to critical stenosis of both anterior cerebral arteries (ACA). Despite the quick surgical decompression and consequent blood flow restoration, the neurological conditions of the patient did not improve and she died 18 days later. Ten other cases of anterior circulation stroke due to PA were retrieved in a systematic review of literature. Clinical and neuroradiological features of these patients and treatment outcome were assessed to suggest the most proper management.
CONCLUSION CONCLUSIONS
The onset of neurological symptoms suggestive for brain stroke in patients with PA requires performing an emergency Magnetic Resonance Imaging (MRI), including Diffusion-weighted and angiographic MR-sequences. The role of surgery in these cases is debated, however, transsphenoidal adenomectomy would permit us to decompress the ACA and restore blood flow in their territories. Although the prognosis of PA-induced anterior circulation stroke is generally poor, a timely diagnosis and treatment would be paramount for improving patient outcome.

Identifiants

pubmed: 35343284
doi: 10.1177/19714009221083146
pmc: PMC10649528
doi:

Types de publication

Systematic Review Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

746-751

Déclaration de conflit d'intérêts

Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Références

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Auteurs

Matteo Zoli (M)

Programma Neurochirurgia Ipofisi- Pituitary Unit, IRCCS Istituto delle Scienze Neurologiche di Bologna, Italy.
Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Italy.

Federica Guaraldi (F)

Programma Neurochirurgia Ipofisi- Pituitary Unit, IRCCS Istituto delle Scienze Neurologiche di Bologna, Italy.

Arianna Rustici (A)

Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Italy.

Luigi Cirillo (L)

Programma Neurochirurgia Ipofisi- Pituitary Unit, IRCCS Istituto delle Scienze Neurologiche di Bologna, Italy.
Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Italy.

Sofia Asioli (S)

Programma Neurochirurgia Ipofisi- Pituitary Unit, IRCCS Istituto delle Scienze Neurologiche di Bologna, Italy.
Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Italy.

Diego Mazzatenta (D)

Programma Neurochirurgia Ipofisi- Pituitary Unit, IRCCS Istituto delle Scienze Neurologiche di Bologna, Italy.
Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Italy.

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