Synchronous Fluorescence as a Green and Selective Method for the Simultaneous Determination of Cetirizine and Azelastine in Aqueous Humor.
Aqueous humor
Azelastine
Cetirizine
Eye Drops
Synchronous Fluorimetry
Journal
Journal of fluorescence
ISSN: 1573-4994
Titre abrégé: J Fluoresc
Pays: Netherlands
ID NLM: 9201341
Informations de publication
Date de publication:
May 2022
May 2022
Historique:
received:
18
01
2022
accepted:
25
02
2022
pubmed:
29
3
2022
medline:
17
5
2022
entrez:
28
3
2022
Statut:
ppublish
Résumé
A green, simple, quick and economical method is implemented for the first time for the simultaneous estimation of cetirizine (CTZ) and azelastine (AZE) as co-administered eye drops. The method relies on synchronous spectrofluorimetry with ∆λ = 60 nm. Cetirizine can be estimated at 231 nm and AZE can be measured at 294 nm, each at the other's zero crossing point. All factors affecting the method were studied and properly optimized. Good correlation was obtained in the range of 0.1-2 µg mL
Identifiants
pubmed: 35344122
doi: 10.1007/s10895-022-02913-6
pii: 10.1007/s10895-022-02913-6
pmc: PMC9095524
doi:
Substances chimiques
Ophthalmic Solutions
0
Phthalazines
0
Cetirizine
YO7261ME24
azelastine
ZQI909440X
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1199-1210Informations de copyright
© 2022. The Author(s).
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