Coronary Artery Disease and Aspirin Intolerance: Background and Insights on Current Management.

Acute coronary syndrome Aspirin intolerance Coronary artery disease

Journal

Cardiology and therapy
ISSN: 2193-8261
Titre abrégé: Cardiol Ther
Pays: England
ID NLM: 101634495

Informations de publication

Date de publication:
Jun 2022
Historique:
received: 05 01 2022
pubmed: 29 3 2022
medline: 29 3 2022
entrez: 28 3 2022
Statut: ppublish

Résumé

Aspirin is one of the most widely used medications across the global healthcare system and is the foundation in treating ischemic heart disease, as well as secondary prevention for ischemic and valvular heart disease. Challenges arise in treating patients with cardiovascular disease who have concomitant aspirin intolerance. Through an extensive review of the literature, we provide a comprehensive background on the pharmacology of aspirin, the mechanisms behind aspirin intolerance, the importance of aspirin in cardiovascular disease, and the management of aspirin intolerance in both acute coronary syndrome and stable coronary artery disease. Our review includes a multidisciplinary approach from the internist, allergist/immunologist, and cardiologist when evaluating this important patient population.

Identifiants

pubmed: 35344187
doi: 10.1007/s40119-022-00255-9
pii: 10.1007/s40119-022-00255-9
pmc: PMC9135937
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

175-183

Informations de copyright

© 2022. The Author(s).

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Auteurs

Ravi A Thakker (RA)

Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, 77555, USA. ravi.a.thakker@gmail.com.

Leonardo Salazar (L)

Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, 77555, USA.

Deaa Abu Jazar (DA)

Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, 77555, USA.

Pooja Bhakta (P)

Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, 77555, USA.

Bryan Baker (B)

Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, 77555, USA.

Chandani Patel (C)

Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, 77555, USA.

Ayman Elbadawi (A)

Division of Cardiology, Department of Medicine, Baylor College of Medicine, Houston, TX, USA.

Mayank Agarwal (M)

Division of Cardiology, University of Texas Medical Branch, Galveston, TX, USA.

Aiham Albaeni (A)

Division of Cardiology, University of Texas Medical Branch, Galveston, TX, USA.

Mohammed Saleh (M)

Division of Cardiology, University of Texas Medical Branch, Galveston, TX, USA.

Jonathan Esclovan (J)

Division of Cardiology, University of Texas Medical Branch, Galveston, TX, USA.

Danielle El Haddad (D)

Division of Cardiology, University of Texas Medical Branch, Galveston, TX, USA.

Hashim Alwash (H)

Division of Cardiology, University of Texas Medical Branch, Galveston, TX, USA.

Ankur Kalra (A)

Division of Cardiovascular Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.

Sachin S Goel (SS)

Department of Cardiology, Houston Methodist DeBakey Heart and Vascular Center, Houston, TX, USA.

Robert Jay Widmer (RJ)

Division of Cardiology, Scott and White Heart Memorial Hospital, Baylor Scott and White Health, Temple, TX, USA.

Khaled Chatila (K)

Division of Cardiology, University of Texas Medical Branch, Galveston, TX, USA.

Wissam Khalife (W)

Division of Cardiology, University of Texas Medical Branch, Galveston, TX, USA.

Afaq Motiwala (A)

Division of Cardiology, University of Texas Medical Branch, Galveston, TX, USA.

Jennifer McCracken (J)

Division of Allergy and Immunology, University of Texas Medical Branch, Galveston, TX, USA.

Hani Jneid (H)

Division of Cardiology, Department of Medicine, Baylor College of Medicine, Houston, TX, USA.

Syed Gilani (S)

Division of Cardiology, University of Texas Medical Branch, Galveston, TX, USA.

Classifications MeSH