The orbitofrontal cortex of the sheep. Topography, organization, neurochemistry, digital tensor imaging and comparison with the chimpanzee and human.
Chimpanzee
DTI
Human
Orbitofrontal cortex
Sheep
Journal
Brain structure & function
ISSN: 1863-2661
Titre abrégé: Brain Struct Funct
Pays: Germany
ID NLM: 101282001
Informations de publication
Date de publication:
Jun 2022
Jun 2022
Historique:
received:
18
12
2021
accepted:
24
02
2022
pubmed:
30
3
2022
medline:
18
5
2022
entrez:
29
3
2022
Statut:
ppublish
Résumé
Areas dedicated to higher brain functions such as the orbitofrontal cortex (OFC) are thought to be unique to hominidae. The OFC is involved in social behavior, reward and punishment encoding and emotional control. Here, we focused on the putative corresponding area in the sheep to assess its homology to the OFC in humans. We used classical histology in five sheep (Ovis aries) and four chimpanzees (Pan troglodytes) as a six-layered-cortex primate, and Diffusion Tensor Imaging (DTI) in three sheep and five human brains. Nissl's staining exhibited a certain alteration in cortical lamination since no layer IV was found in the sheep. A reduction of the total cortical thickness was also evident together with a reduction of the prevalence of layer one and an increased layer two on the total thickness. Tractography of the sheep OFC, on the other hand, revealed similarities both with human tracts and those described in the literature, as well as a higher number of cortico-cortical fibers connecting the OFC with the visual areas in the right hemisphere. Our results evidenced the presence of the basic components necessary for complex abstract thought in the sheep and a pronounced laterality, often associated with greater efficiency of a certain function, suggested an evolutionary adaptation of this prey species.
Identifiants
pubmed: 35347401
doi: 10.1007/s00429-022-02479-w
pii: 10.1007/s00429-022-02479-w
pmc: PMC9098624
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1871-1891Subventions
Organisme : Ministero dell'Istruzione, dell'Università e della Ricerca
ID : 2015Y5W9YP
Informations de copyright
© 2022. The Author(s).
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