Association between sleep disturbances and pain subtypes in Parkinson's disease.
King’s Parkinson’s disease Pain Scale
Pain
Parkinson’s disease
Pittsburgh Sleep Quality Index
Journal
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
ISSN: 1590-3478
Titre abrégé: Neurol Sci
Pays: Italy
ID NLM: 100959175
Informations de publication
Date de publication:
Aug 2022
Aug 2022
Historique:
received:
28
12
2021
accepted:
19
03
2022
pubmed:
30
3
2022
medline:
6
8
2022
entrez:
29
3
2022
Statut:
ppublish
Résumé
To explore the influence of sleep disturbances on the various pain subtypes experienced by patients with Parkinson's disease (PD). A cohort of eighty-eight patients with PD-related pain was recruited for this study. Their demographic and clinical features, including age, disease duration, levodopa equivalent daily dose (LEDD), and scores on the Unified Parkinson's Disease Rating Scale-III (UPDRS III), Hoehn-Yahr Scale (H&Y), Pittsburgh Sleep Quality Index (PSQI), King's Parkinson's disease Pain Scale (KPPS), visual analog scale (VAS), Mini-Mental State Examination (MMSE), activities of daily living scale (ADL), Hamilton Depression Rating Scale (HAMD), and Hamilton Anxiety Rating Scale (HAMA), were recorded. The prevalence of sleep disorders was 76.1% in patients with PD-related pain. Among these patients, the group of poor sleep had more severe motor symptoms, more anxiety and depression symptoms, lower functional independence, and experienced more pain, such as musculoskeletal pain, chronic pain, fluctuation related pain, nocturnal pain, and discoloration/edema/swelling (p < 0.05). In addition, PSQI scores correlated positively with the scores of all 7 domains in KPPS (p < 0.05). H&Y stage and PSQI were significant independent variables explaining 50.0% of the variance in KPPS scores. Sleep disturbance showed an association with pain in PD patients and may have a greater effect on some certain subtypes of PD-related pain than others.
Identifiants
pubmed: 35347526
doi: 10.1007/s10072-022-06030-x
pii: 10.1007/s10072-022-06030-x
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
4785-4790Subventions
Organisme : Key Research and Development Program of Jiangxi Province
ID : 20202BBGL73104
Informations de copyright
© 2022. Fondazione Società Italiana di Neurologia.
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