Distinct Neural Profiles of Frontoparietal Networks in Boys with ADHD and Boys with Persistent Depressive Disorder.
Attention-deficit/hyperactivity disorder
Children
Depression
Multivariate pattern analysis
Working memory
fMRI
Journal
Cognitive, affective & behavioral neuroscience
ISSN: 1531-135X
Titre abrégé: Cogn Affect Behav Neurosci
Pays: United States
ID NLM: 101083946
Informations de publication
Date de publication:
10 2022
10 2022
Historique:
accepted:
12
03
2022
pubmed:
30
3
2022
medline:
14
9
2022
entrez:
29
3
2022
Statut:
ppublish
Résumé
Working memory deficits are common in attention-deficit/hyperactivity disorder (ADHD) and depression-two common neurodevelopmental disorders with overlapping cognitive profiles but distinct clinical presentation. Multivariate techniques have previously been utilized to understand working memory processes in functional brain networks in healthy adults but have not yet been applied to investigate how working memory processes within the same networks differ within typical and atypical developing populations. We used multivariate pattern analysis (MVPA) to identify whether brain networks discriminated between spatial versus verbal working memory processes in ADHD and Persistent Depressive Disorder (PDD). Thirty-six male clinical participants and 19 typically developing (TD) boys participated in a fMRI scan while completing a verbal and a spatial working memory task. Within a priori functional brain networks (frontoparietal, default mode, salience), the TD group demonstrated differential response patterns to verbal and spatial working memory. The PDD group showed weaker differentiation than TD, with lower classification accuracies observed in primarily the left frontoparietal network. The neural profiles of the ADHD and PDD differed specifically in the SN where the ADHD group's neural profile suggests significantly less specificity in neural representations of spatial and verbal working memory. We highlight within-group classification as an innovative tool for understanding the neural mechanisms of how cognitive processes may deviate in clinical disorders, an important intermediary step towards improving translational psychiatry.
Identifiants
pubmed: 35349053
doi: 10.3758/s13415-022-00999-w
pii: 10.3758/s13415-022-00999-w
pmc: PMC10149107
mid: NIHMS1884784
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1183-1198Subventions
Organisme : NIDA NIH HHS
ID : F31 DA042574
Pays : United States
Informations de copyright
© 2022. The Psychonomic Society, Inc.
Références
JAMA Psychiatry. 2015 Oct;72(10):1045-53
pubmed: 26332700
Eur Child Adolesc Psychiatry. 2015 Apr;24(4):365-84
pubmed: 25633323
Curr Opin Neurobiol. 2020 Dec;65:120-128
pubmed: 33242721
Nat Neurosci. 2017 Feb 23;20(3):365-377
pubmed: 28230847
Neuroimage. 2009 Mar;45(1 Suppl):S199-209
pubmed: 19070668
J Affect Disord. 2008 Nov;111(1):113-8
pubmed: 18367251
Hum Brain Mapp. 2009 Jul;30(7):2252-66
pubmed: 19107748
Magn Reson Imaging. 2008 Sep;26(7):1007-14
pubmed: 18691999
Biol Psychol. 2016 Oct;120:10-20
pubmed: 27481545
Neuroimage. 2018 Aug 1;176:110-123
pubmed: 29654876
World Psychiatry. 2007 Oct;6(3):168-76
pubmed: 18188442
Biol Psychiatry. 2003 Mar 1;53(5):376-84
pubmed: 12614990
Cereb Cortex. 2016 Apr;26(4):1501-1511
pubmed: 25596593
Cortex. 2010 Jul-Aug;46(7):880-95
pubmed: 19811779
Neuroreport. 2006 May 29;17(8):843-6
pubmed: 16708026
Cereb Cortex. 2016 Apr;26(4):1647-59
pubmed: 25601237
Biol Psychiatry. 2010 Apr 1;67(7):632-40
pubmed: 20060961
Neuroimage. 2014 Apr 1;89:345-57
pubmed: 24296330
J Am Acad Child Adolesc Psychiatry. 2012 Apr;51(4):356-67
pubmed: 22449642
J Cogn Neurosci. 2009 Feb;21(2):316-32
pubmed: 18510448
J Affect Disord. 2009 Jul;116(1-2):100-5
pubmed: 19042027
Mol Psychiatry. 2007 Feb;12(2):158-66
pubmed: 16983390
Child Psychiatry Hum Dev. 2021 Oct;52(5):800-807
pubmed: 32951164
Mol Psychiatry. 2021 Aug;26(8):4016-4025
pubmed: 31664176
J Affect Disord. 2011 Oct;133(3):625-32
pubmed: 21620477
Trends Cogn Sci. 2011 Oct;15(10):483-506
pubmed: 21908230
Front Syst Neurosci. 2013 Feb 04;6:80
pubmed: 23382713
Biol Psychiatry. 2008 Dec 15;64(12):1035-41
pubmed: 18822407
J Am Acad Child Adolesc Psychiatry. 2005 Apr;44(4):377-84
pubmed: 15782085
Br J Psychiatry. 2005 Sep;187:282-3
pubmed: 16135867
Neuroimage. 2005 Jan 15;24(2):462-72
pubmed: 15627588
J Am Acad Child Adolesc Psychiatry. 2001 Aug;40(8):937-44
pubmed: 11501694
Child Neuropsychol. 2005 Apr;11(2):153-73
pubmed: 16036442
Psychol Med. 2014 Feb;44(3):633-46
pubmed: 23597077
Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 Aug;5(8):791-798
pubmed: 31982357
Biol Psychiatry. 2005 Jun 1;57(11):1336-46
pubmed: 15950006
Neuron. 2015 Jul 15;87(2):257-70
pubmed: 26182413
Brain. 2006 Mar;129(Pt 3):564-83
pubmed: 16399806
Neuroimage. 2005 Jul 1;26(3):860-9
pubmed: 15955496
Mol Psychiatry. 2007 Sep;12(9):826-32, 793
pubmed: 17471290
J Cogn Neurosci. 2015 Oct;27(10):1895-911
pubmed: 26058604
Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):13040-5
pubmed: 19620724
Neuroimage. 2016 May 15;132:32-42
pubmed: 26899782
BMC Med. 2013 May 14;11:126
pubmed: 23672542
Neuroimage. 2006 Jan 1;29(1):203-15
pubmed: 16157491
J Affect Disord. 2007 Aug;101(1-3):175-85
pubmed: 17197035
Brain Cogn. 2013 Jun;82(1):58-68
pubmed: 23511846
Eur Arch Psychiatry Clin Neurosci. 2011 Apr;261(3):179-84
pubmed: 21063718
Comput Biomed Res. 1996 Jun;29(3):162-73
pubmed: 8812068
Nord J Psychiatry. 2002;56(3):187-93
pubmed: 12079570
J Neurosci. 2015 Sep 9;35(36):12355-65
pubmed: 26354905
Nat Neurosci. 2016 Mar;19(3):404-13
pubmed: 26906507
Neuroimage. 2018 Oct 15;180(Pt A):4-18
pubmed: 28782682
Inf Process Med Imaging. 2003 Jul;18:330-41
pubmed: 15344469
J Am Acad Child Adolesc Psychiatry. 2016 Nov;55(11):937-944.e4
pubmed: 27806861
J Atten Disord. 2011 Aug;15(6):461-72
pubmed: 20574057
Cereb Cortex. 2008 Jun;18(6):1421-8
pubmed: 17947348
Neuroimage. 2020 Jun;213:116731
pubmed: 32173409
Neurosci Bull. 2012 Aug;28(4):399-408
pubmed: 22833038
J Child Psychol Psychiatry. 2016 Mar;57(3):321-49
pubmed: 26705858
Can J Psychiatry. 2009 Oct;54(10):665-72
pubmed: 19835673
Science. 1999 Mar 12;283(5408):1657-61
pubmed: 10073923
J Abnorm Child Psychol. 1998 Aug;26(4):257-68
pubmed: 9700518
Br J Clin Psychol. 2010 Jun;49(Pt 2):235-58
pubmed: 19646334
Front Hum Neurosci. 2014 Jan 21;7:930
pubmed: 24478665
Annu Rev Clin Psychol. 2018 May 7;14:91-118
pubmed: 29401044
J Am Acad Child Adolesc Psychiatry. 2007 Nov;46(11):1437-44
pubmed: 18049293
Am J Psychiatry. 2014 Mar;171(3):276-93
pubmed: 24480998
Am J Psychiatry. 2012 Oct;169(10):1038-55
pubmed: 22983386
J Abnorm Child Psychol. 2013 Oct;41(7):1027-39
pubmed: 23624770
Front Neuroinform. 2015 Jan 06;8:88
pubmed: 25610393
AJNR Am J Neuroradiol. 2014 May;35(5):848-55
pubmed: 24029388
Lancet Psychiatry. 2016 May;3(5):425-35
pubmed: 26995298
Neuroimage. 2012 Feb 1;59(3):2636-43
pubmed: 21924359
J Affect Disord. 2004 Oct 15;82(2):265-9
pubmed: 15488256
Annu Rev Neurosci. 2014;37:435-56
pubmed: 25002277
Brain Struct Funct. 2010 Jun;214(5-6):655-67
pubmed: 20512370
Child Dev Perspect. 2008 Dec 1;2(3):149-155
pubmed: 20721304
J Neurosci. 2019 Dec 11;39(50):9878-9882
pubmed: 31676604
Am J Psychiatry. 2000 Jun;157(6):931-9
pubmed: 10831473
Neuroimage. 2012 Mar;60(1):830-46
pubmed: 22178808
Nervenarzt. 2007 Jun;78(6):628, 630-2, 634-6 passim
pubmed: 17279398
Neurosci Biobehav Rev. 2018 Sep;92:464-476
pubmed: 30036553
Neurosci Biobehav Rev. 2007;31(7):977-86
pubmed: 17445893
Neuron. 2012 Jun 21;74(6):990-1004
pubmed: 22726830
Neuron. 2014 Jul 2;83(1):238-51
pubmed: 24991964
J Affect Disord. 2014 May;160:34-42
pubmed: 24709020
J Psychiatr Res. 2019 Mar;110:51-56
pubmed: 30594024
Front Psychiatry. 2012 Jan 25;3:2
pubmed: 22291667
Neuroimage Clin. 2021;30:102593
pubmed: 33647810
Psychol Med. 2010 Feb;40(2):253-61
pubmed: 19607749
Annu Rev Neurosci. 2019 Jul 8;42:407-432
pubmed: 31283895
Neuroimage. 2021 Jul 1;234:117965
pubmed: 33744454