Acute autonomic dysregulation due to HHV-6 encephalitis in an immunocompromised patient: a case report and literature review.
Autonomic dysfunction
Foscarnet
Ganciclovir
HHV-6 encephalitis Immunocompromised
Stem cell transplantation
Journal
Acta neurologica Belgica
ISSN: 2240-2993
Titre abrégé: Acta Neurol Belg
Pays: Italy
ID NLM: 0247035
Informations de publication
Date de publication:
Jun 2022
Jun 2022
Historique:
received:
12
08
2021
accepted:
21
10
2021
pubmed:
30
3
2022
medline:
9
6
2022
entrez:
29
3
2022
Statut:
ppublish
Résumé
Human herpesvirus-6 (HHV-6), in particularly HHV-6B, can reactivate in immunocompromised patients. Especially after stem cell transplantation, reactivation of HHV-6 can cause complications, such as limbic encephalitis. We present a case of a 61-year-old man with B-cell non-Hodgkin lymphoma. He presented with subacute lethargy, confusion and hyperhidrosis. Following this, we will give a short review of the literature considering clinical and technical features as well as treatment options.
Identifiants
pubmed: 35349121
doi: 10.1007/s13760-021-01828-6
pii: 10.1007/s13760-021-01828-6
doi:
Types de publication
Case Reports
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
583-585Informations de copyright
© 2022. The Author(s) under exclusive licence to Belgian Neurological Society.
Références
Baldwin KJ, Cummings CL (2018) Herpesvirus infections of the nervous system. Continuum (Minneap Minn). 24:1349–1369
pubmed: 30273243
Bhanushali MJ, Kranick SM, Freeman AF, Cuellar-Rodriguez JM, Battiwalla M, Gea-Banacloche JC et al (2013) Human herpes 6 virus encephalitis complicating allogeneic hematopoietic stem cell transplantation. Neurology 80(16):1494–1500
doi: 10.1212/WNL.0b013e31828cf8a2
Frey JW, Cherabie JN, Assi MA (2017) Human herpesvirus-6 encephalitis following chemotherapy induction for acute myelogenous leukemia. Transpl Infect Dis 19(6):1–4
doi: 10.1111/tid.12756
Hill JA (2019) Human herpesvirus 6 in transplant recipients: an update on diagnostic and treatment strategies. Curr Opin Infect Dis 32(6):584–590
doi: 10.1097/QCO.0000000000000592
Ward KN, Hill JA, Hubacek P, de la Camara R, Crocchiolo R, Einsele H et al (2019) Guidelines from the 2017 European Conference on Infections in Leukaemia for management of HHV-6 infection in patients with hematologic malignancies and after hematopoietic stem cell transplantation. Haematologica 104(11):2155–2163
doi: 10.3324/haematol.2019.223073