Synchronous spiking of cerebellar Purkinje cells during control of movements.
Purkinje cells
cerebellum
movement
saccades
synchrony
Journal
Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876
Informations de publication
Date de publication:
05 04 2022
05 04 2022
Historique:
entrez:
29
3
2022
pubmed:
30
3
2022
medline:
6
5
2022
Statut:
ppublish
Résumé
SignificanceThe information that one region of the brain transmits to another is usually viewed through the lens of firing rates. However, if the output neurons could vary the timing of their spikes, then, through synchronization, they would spotlight information that may be critical for control of behavior. Here we report that, in the cerebellum, Purkinje cell populations that share a preference for error convey, to the nucleus, when to decelerate the movement, by reducing their firing rates and temporally synchronizing the remaining spikes.
Identifiants
pubmed: 35349338
doi: 10.1073/pnas.2118954119
pmc: PMC9168948
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2118954119Subventions
Organisme : NIBIB NIH HHS
ID : R01 EB028156
Pays : United States
Commentaires et corrections
Type : CommentIn
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