Oral appliance therapy for obstructive sleep apnea in multiple system atrophy with floppy epiglottis: a case series of three patients.

Floppy epiglottis Multiple system atrophy Obstructive sleep apnea Oral appliance

Journal

Sleep & breathing = Schlaf & Atmung
ISSN: 1522-1709
Titre abrégé: Sleep Breath
Pays: Germany
ID NLM: 9804161

Informations de publication

Date de publication:
03 2023
Historique:
received: 18 01 2022
accepted: 22 03 2022
revised: 07 03 2022
pubmed: 31 3 2022
medline: 10 3 2023
entrez: 30 3 2022
Statut: ppublish

Résumé

A recent study demonstrated that continuous positive airway pressure (CPAP) may exacerbate obstructive sleep apnea (OSA) in patients with multiple system atrophy (MSA) and a floppy epiglottis (FE) as the CPAP promotes downward displacement of the epiglottis into the laryngeal inlet. In this case series, we examined the effectiveness of an oral appliance (OA) for treating OSA in three patients with MSA and an FE. Patients with MSA were demonstrated to have an FE on fiberoptic laryngoscopy under sedation using intravenous propofol. The therapeutic intervention was fitting an OA. Polysomnography (PSG) was performed subsequently with the OA in place. In three patients with MSA, some parameters used to assess the severity of OSA improved with an OA. Both apnea-hypopnea index (AHI) and arousal index (ArI) decreased while wearing the OA in two cases while in the third case, apnea index (AI) and cumulative time at peripheral oxygen saturation (SpO OA therapy using a two-piece type mandibular advancement device (MAD) may be a useful treatment intervention for patients with OSA who have MSA and FE.

Identifiants

pubmed: 35352265
doi: 10.1007/s11325-022-02607-0
pii: 10.1007/s11325-022-02607-0
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

213-219

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer Nature Switzerland AG.

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Auteurs

Toshihiko Mikami (T)

Division of Reconstructive Surgery for Oral and Maxillofacial Region, Faculty of Dentistry & Graduate School of Medical and Dental Sciences, Niigata University, 2-5274 Gakkocho-Dori, Chuo-ku, Niigata, 951-8514, Japan. t-mikami@dent.niigata-u.ac.jp.
Department of Dentistry and Oral Surgery, Niigata Medical Center, Niigata, Japan. t-mikami@dent.niigata-u.ac.jp.

Tadaharu Kobayashi (T)

Division of Reconstructive Surgery for Oral and Maxillofacial Region, Faculty of Dentistry & Graduate School of Medical and Dental Sciences, Niigata University, 2-5274 Gakkocho-Dori, Chuo-ku, Niigata, 951-8514, Japan.

Daichi Hasebe (D)

Division of Reconstructive Surgery for Oral and Maxillofacial Region, Faculty of Dentistry & Graduate School of Medical and Dental Sciences, Niigata University, 2-5274 Gakkocho-Dori, Chuo-ku, Niigata, 951-8514, Japan.

Yasuyoshi Ohshima (Y)

Department of Respiratory Medicine and Infectious Diseases, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

Tetsuya Takahashi (T)

Department of Neurology, National Hospital Organization Nishiniigata Chuo Hospital, Niigata, Japan.

Takayoshi Shimohata (T)

Department of Neurology, Gifu University Graduate School of Medicine, Gifu, Japan.

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