Relative expression of aromatase in the male goat reproductive organs during different seasons.
androgen
aromatase
breeding and nonbreeding seasons
male goat
qRT-PCR
Journal
Reproduction in domestic animals = Zuchthygiene
ISSN: 1439-0531
Titre abrégé: Reprod Domest Anim
Pays: Germany
ID NLM: 9015668
Informations de publication
Date de publication:
Jul 2022
Jul 2022
Historique:
received:
20
01
2022
accepted:
27
03
2022
pubmed:
31
3
2022
medline:
14
7
2022
entrez:
30
3
2022
Statut:
ppublish
Résumé
Aromatase, a member of the cytochrome P450 superfamily (encoded by CYP19), is the enzyme responsible for the aromatization of androgens into estrogens which is the last step of estrogen biosynthesis. It plays an important role in reproduction and sexual development. The aromatase expression in many tissues and organs of different species is shown in the last two decades' investigation. This study was conducted to determine the relative seasonal expression of aromatase mRNA in testis, epididymis, vas deferens, prostate and seminal vesicle of a male goat. The aromatase expression of 16 male goat reproductive organs, slaughtered in the different seasons (n = 4 each season), were determined by quantitative real-time polymerase chain reaction (qRT-PCR). Results showed that during the autumn, aromatase mRNA expression of the testis was found to be significantly higher (p < .05) as compared to the spring and summer seasons. Higher aromatase mRNA expression was also found in the epididymis and seminal vesicle organs during the autumn and summer seasons. Interestingly, prostate and vas deferens aromatase mRNA expression during the summer was higher than in other seasons. The aromatase mRNA level analysis revealed that aromatase is expressed in all the examined reproductive organs in which a strong expression signal was detected in the testis and epididymis tissues. This study shows the expression of the aromatase in the goat reproductive organs in the breeding season which resembles other mammals with continuous breeding.
Substances chimiques
RNA, Messenger
0
Aromatase
EC 1.14.14.1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
806-812Informations de copyright
© 2022 Wiley-VCH GmbH.
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