Fosfomycin Susceptibility Testing Using Commercial Agar Dilution Test.


Journal

Microbiology spectrum
ISSN: 2165-0497
Titre abrégé: Microbiol Spectr
Pays: United States
ID NLM: 101634614

Informations de publication

Date de publication:
27 04 2022
Historique:
pubmed: 31 3 2022
medline: 30 4 2022
entrez: 30 3 2022
Statut: ppublish

Résumé

The reference standard for fosfomycin antimicrobial susceptibility testing (AST) is agar dilution, but it is laborious and is not routinely used in diagnostic microbiology. In this study, we evaluated the performance of a ready-to-use commercially available agar dilution kit for fosfomycin AST (Liofilchem Diagnostics). We compared this kit with the reference standard agar dilution, performed according to the Clinical & Laboratory Standards Institute (CLSI) in 229 clinical isolates. The isolates were selected to represent both Gram-positive and Gram-negative microorganisms, with various MIC values. It consisted of 43 enterococci (E. faecalis

Identifiants

pubmed: 35352940
doi: 10.1128/spectrum.02504-21
pmc: PMC9045359
doi:

Substances chimiques

Anti-Bacterial Agents 0
Fosfomycin 2N81MY12TE
Agar 9002-18-0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0250421

Références

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Auteurs

Peter D Croughs (PD)

Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, Rotterdam, the Netherlands.

Michelle Konijnendijk-de Regt (M)

Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, Rotterdam, the Netherlands.

Erlangga Yusuf (E)

Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, Rotterdam, the Netherlands.

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Classifications MeSH