Anatomic position determines oncogenic specificity in melanoma.

Animals Animals, Genetically Modified Carcinogenesis / genetics Foot Hand Humans Melanoma / pathology Nails Oncogenes / genetics Skin Neoplasms / genetics Transcription, Genetic Zebrafish / genetics Melanoma, Cutaneous Malignant

Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
04 2022
Historique:
received: 14 11 2020
accepted: 25 02 2022
pubmed: 1 4 2022
medline: 16 4 2022
entrez: 31 3 2022
Statut: ppublish

Résumé

Oncogenic alterations to DNA are not transforming in all cellular contexts

Identifiants

DOI: 10.1038/s41586-022-04584-6 PMID: 35355015 PMC: PMC9355078
pubmed: 35355015
doi: 10.1038/s41586-022-04584-6
pii: 10.1038/s41586-022-04584-6
pmc: PMC9355078
mid: NIHMS1816756
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

354-361

Subventions

Organisme : NCI NIH HHS
ID : F30 CA220954
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA008748
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM008539
Pays : United States
Organisme : Medical Research Council
Pays : United Kingdom
Organisme : NCI NIH HHS
ID : R01 CA238317
Pays : United States
Organisme : NIH HHS
ID : S10 OD010598
Pays : United States
Organisme : NCI NIH HHS
ID : F30 CA236442
Pays : United States
Organisme : NCI NIH HHS
ID : K00 CA223016
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM007739
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA229215
Pays : United States
Organisme : NCI NIH HHS
ID : DP2 CA186572
Pays : United States

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer Nature Limited.

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Auteurs

Joshua M Weiss (JM)

Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, USA.
Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Cell and Developmental Biology Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA.

Miranda V Hunter (MV)

Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
ORCID: 0000-0002-6971-1738

Nelly M Cruz (NM)

Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
ORCID: 0000-0002-9040-6957

Arianna Baggiolini (A)

Developmental Biology, The Center for Stem Cell Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
ORCID: 0000-0002-2476-561X

Mohita Tagore (M)

Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
ORCID: 0000-0002-2586-1427

Yilun Ma (Y)

Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, USA.
Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Cell and Developmental Biology Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA.

Sandra Misale (S)

Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Michelangelo Marasco (M)

Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Theresa Simon-Vermot (T)

Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Nathaniel R Campbell (NR)

Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, USA.
Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Computational and Systems Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Physiology, Biophysics & Systems Biology Graduate Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA.
ORCID: 0000-0002-0355-0708

Felicity Newell (F)

QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
ORCID: 0000-0003-0469-2705

James S Wilmott (JS)

Melanoma Institute Australia, The University of Sydney, Sydney, New South Wales, Australia.

Peter A Johansson (PA)

QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.

John F Thompson (JF)

Melanoma Institute Australia, The University of Sydney, Sydney, New South Wales, Australia.
Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.
Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.
ORCID: 0000-0002-2816-2496

Georgina V Long (GV)

Melanoma Institute Australia, The University of Sydney, Sydney, New South Wales, Australia.
Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.
Royal North Shore Hospital, Sydney, New South Wales, Australia.
ORCID: 0000-0001-8894-3545

John V Pearson (JV)

QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.

Graham J Mann (GJ)

Melanoma Institute Australia, The University of Sydney, Sydney, New South Wales, Australia.
John Curtin School of Medical Research, Australian National University, Acton, Australian Capital Territory, Australia.
Centre for Cancer Research, Westmead Institute for Medical Research, The University of Sydney, Westmead, Sydney, New South Wales, Australia.

Richard A Scolyer (RA)

Melanoma Institute Australia, The University of Sydney, Sydney, New South Wales, Australia.
Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.
Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.
New South Wales Health Pathology, Sydney, New South Wales, Australia.

Nicola Waddell (N)

QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
School of Medicine, The University of Queensland, Brisbane, Queensland, Australia.
ORCID: 0000-0002-3950-2476

Emily D Montal (ED)

Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Ting-Hsiang Huang (TH)

Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Philip Jonsson (P)

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
ORCID: 0000-0002-1537-0624

Mark T A Donoghue (MTA)

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Christopher C Harris (CC)

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Barry S Taylor (BS)

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Tianhao Xu (T)

Computational and Systems Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Ronan Chaligné (R)

Computational and Systems Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
ORCID: 0000-0003-4332-3291

Pavel V Shliaha (PV)

Department of Biochemistry and Molecular Biology, VILLUM Center for Bioanalytical Sciences, University of Southern Denmark, Odense, Denmark.
Microchemistry and Proteomics Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Ronald Hendrickson (R)

Microchemistry and Proteomics Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Achim A Jungbluth (AA)

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Cecilia Lezcano (C)

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Richard Koche (R)

Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
ORCID: 0000-0002-6820-5083

Lorenz Studer (L)

Developmental Biology, The Center for Stem Cell Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
ORCID: 0000-0003-0741-7987

Charlotte E Ariyan (CE)

Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

David B Solit (DB)

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
ORCID: 0000-0002-6614-802X

Jedd D Wolchok (JD)

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
Weill Cornell Medicine, New York, NY, USA.
ORCID: 0000-0001-6718-2222

Taha Merghoub (T)

Weill Cornell Medicine, New York, NY, USA.
ORCID: 0000-0002-1518-5111

Neal Rosen (N)

Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
ORCID: 0000-0002-8307-654X

Nicholas K Hayward (NK)

QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.

Richard M White (RM)

Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, USA. whiter@mskcc.org.
ORCID: 0000-0001-9099-9169

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Anatomic position determines oncogenic...
questionsmedicales.fr › Stades d'organismes › Organismes génétiquement modifiés › Animal génétiquement modifié › Anatomic position determines oncogenic...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Processus néoplasiques › Carcinogenèse › Anatomic position determines oncogenic...
questionsmedicales.fr › Régions du corps › Membres › Membre inférieur › Pied › Anatomic position determines oncogenic...
questionsmedicales.fr › Régions du corps › Membres › Membre supérieur › Main › Anatomic position determines oncogenic...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Anatomic position determines oncogenic...
questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Naevus et mélanomes › Mélanome › Anatomic position determines oncogenic...
questionsmedicales.fr › Système tégumentaire › Ongles › Anatomic position determines oncogenic...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Gènes › Gènes tumoraux › Oncogènes › Anatomic position determines oncogenic...
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies de la peau › Tumeurs cutanées › Anatomic position determines oncogenic...
questionsmedicales.fr › Phénomènes génétiques › Expression des gènes › Transcription génétique › Anatomic position determines oncogenic...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Poissons › Cypriniformes › Cyprinidae › Danio zébré › Anatomic position determines oncogenic...