T-Cell Responses to Immunodominant Listeria Epitopes Limit Vaccine-Directed Responses to the Colorectal Cancer Antigen, Guanylyl Cyclase C.


Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2022
Historique:
received: 15 01 2022
accepted: 10 02 2022
entrez: 31 3 2022
pubmed: 1 4 2022
medline: 9 4 2022
Statut: epublish

Résumé

The Gram-positive bacterium

Identifiants

pubmed: 35355987
doi: 10.3389/fimmu.2022.855759
pmc: PMC8959893
doi:

Substances chimiques

Cancer Vaccines 0
Epitopes 0
Immunodominant Epitopes 0
Peptides 0
GUCY2C protein, human EC 4.6.1.2
Receptors, Enterotoxin EC 4.6.1.2

Types de publication

Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

855759

Subventions

Organisme : NIDDK NIH HHS
ID : F30 DK127639
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA204481
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA206026
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA056036
Pays : United States

Informations de copyright

Copyright © 2022 Flickinger, Singh, Yarman, Carlson, Barton, Waldman and Snook.

Déclaration de conflit d'intérêts

SW is a member of the Board and Chair of the Scientific Advisory Board of, and AS is a consultant for, Targeted Diagnostics & Therapeutics, Inc., which provided research funding that, in part, supported this work and has a license to commercialize inventions related to this work. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

John C Flickinger (JC)

Department of Pharmacology & Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA, United States.

Jagmohan Singh (J)

Department of Pharmacology & Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA, United States.

Yanki Yarman (Y)

Department of Pharmacology & Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA, United States.

Robert D Carlson (RD)

Department of Pharmacology & Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA, United States.

Joshua R Barton (JR)

Department of Pharmacology & Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA, United States.

Scott A Waldman (SA)

Department of Pharmacology & Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA, United States.
Sidney Kimmel Cancer Center, Philadelphia, PA, United States.

Adam E Snook (AE)

Department of Pharmacology & Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA, United States.
Sidney Kimmel Cancer Center, Philadelphia, PA, United States.
Department of Microbiology & Immunology, Thomas Jefferson University, Philadelphia, PA, United States.

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Classifications MeSH