The Diagnostic Value of Contrast Enhanced Ultrasound for Localization of Parathyroid Lesions in Primary Hyperparathyroidism: Comparison With Color Doppler Ultrasound: Comparison With Color Doppler Ultrasound.


Journal

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
ISSN: 1550-9613
Titre abrégé: J Ultrasound Med
Pays: England
ID NLM: 8211547

Informations de publication

Date de publication:
Jan 2023
Historique:
revised: 18 01 2022
received: 26 10 2021
accepted: 21 03 2022
pubmed: 1 4 2022
medline: 22 12 2022
entrez: 31 3 2022
Statut: ppublish

Résumé

Preoperative localization of pathological parathyroid glands with imaging is essential for focused unilateral neck exploration and minimally invasive techniques. Recently published studies suggested that contrast-enhanced ultrasonography (CEUS) had high accuracy in the localization of hyperfunctioning parathyroid glands, with a general increase in the sensitivity as compared to conventional sonography. The purpose of this study was to determine the usefulness of CEUS in the localization of parathyroid lesions relating to surgical and histopathological data, in comparison to color Doppler ultrasound (CDUS), in the same series of patients. Records of 142 patients who underwent parathyroidectomy were retrospectively examined comparing imaging and intraoperative/histopathologic findings. The overall sensitivity of CEUS was 77.6% compared with 74.6% for CDUS, although no significative differences were found (P = .516). Conversely, CDUS has shown higher sensitivity than CEUS in the group of patients with associated thyroid pathology but there was no statistical difference (P = .529). The sensitivity for detection of multiple adenomas was the same for both procedures. We found no significative superior sensitivity of CEUS also in case of concomitant thyroid pathology and multiple glands disease.

Identifiants

pubmed: 35357028
doi: 10.1002/jum.15984
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

91-98

Informations de copyright

© 2022 American Institute of Ultrasound in Medicine.

Références

Johnson NA, Tublin ME, Ogilvie JB. Parathyroid imaging: technique and role in the preoperative evaluation of primary hyperparathyroidism. Am J Roentgenol 2007; 188:1706-1715. https://doi.org/10.2214/AJR.06.0938.
Kukora SJ, Zeiger MA. The American association of endocrine surgeons position statement on the diagnosis and management of primary hyperparathyroidism. Endocrine Pract 2005; 11:49-54.
Lee JB, Kim WY, Lee YM. The role of preoperative ultrasonography, computed tomography, and sestamibi scintigraphy localization in secondary hyperparathyroidism. Ann Surg Treat Res 2015; 89:300-305. https://doi.org/10.4174/astr.2015.89.6.300.
Thanseer N, Bhadada SK, Sood A, Mittal BR, Behera A, Gorla AKR. Comparative effectiveness of ultrasonography, 99mTc-sestamibi, and 18F-fluorocholine PET/CT in detecting parathyroid adenomas in patients with primary hyperparathyroidism. Clin Nucl Med 2017; 42:491-497. https://doi.org/10.1097/RLU.0000000000001845.
Agha A, Hornung M, Schlitt HJ, Stroszczynski C, Jung EM. The role of contrast-enhancend ultrasonography (CEUS) in comparison with 99mTechnetium-sestamibi scintigraphy for localization diagnostic of primary hyperparathyroidism. Clin Hemorheol Microcirc 2014; 58:515-520.
Agha A, Hornung M, Rennert J, et al. Contrast-enhanced ultrasonography for localization of pathologic glands in patients with primary hyperparathyroidism. Surgery 2012; 151:580-586. https://doi.org/10.1016/j.surg.2011.08.010.
Claudon M, Cosgrove D, Albrecht T, et al. Guidelines and good clinical practice recommendations for contrast enhanced ultrasound (CEUS) - update 2008. Ultraschall Med 2008; 29:28-44. https://doi.org/10.1055/s-2007-963785.
Riss P, Dunkler D, Selberherr A, Brammen L, Heidtmann J, Scheuba C. Evaluating a shortened interpretation criterion for intraoperative parathyroid hormone monitoring in patients with primary hyperparathyroidism: 5-minutes criterion in primary hyperparathyroidism and intraoperative algorithm. Head Neck 2018; 40:2664-2669. https://doi.org/10.1002/hed.25453.
Lubitz CC, Stephen AE, Hodin RA, Pandharipande P. Preoperative localization strategies for primary hyperparathyroidism: an economic analysis. Ann Surg Oncol 2012; 19:4202-4209. https://doi.org/10.1245/s10434-012-2512-2.
Adler JT, Chen H, Schaefer S, Sippel RS. Does routine use of ultrasound result in additional thyroid procedures in patients with primary hyperparathyroidism? J Am Coll Surg 2010; 211:536-539. https://doi.org/10.1016/j.jamcollsurg.2010.05.015.
Kaur P, Gattani R, Singhal A, Sarin D, Arora S, Mithal A. Impact of preoperative imaging on surgical approach for primary hyperparathyroidism: data from single institution in India. Indian J Endocrinol Metab 2016; 20:625-630. https://doi.org/10.4103/2230-8210.190540.
Mahajan A, Starker LF, Ghita M, Udelsman R, Brink JA, Carling T. Parathyroid four-dimensional computed tomography: evaluation of radiation dose exposure during preoperative localization of parathyroid tumors in primary hyperparathyroidism. World J Surg 2012; 36:1335-1339. https://doi.org/10.1007/s00268-011-1365-3.
Bahl M, Sepahdari AR, Sosa JA, Hoang JK. Parathyroid adenomas and hyperplasia on four-dimensional CT scans: three patterns of enhancement relative to the thyroid gland justify a three-phase protocol. Radiology 2015; 277:454-462. https://doi.org/10.1148/radiol.2015142393.
Kim SJ, Lee SW, Jeong SY, Pak K, Kim K. Diagnostic performance of F-18 fluorocholine PET/CT for parathyroid localization in hyperparathyroidism: a systematic review and meta-analysis. Horm Cancer 2018; 9:440-447. https://doi.org/10.1007/s12672-018-0347-4.
Treglia G, Piccardo A, Imperiale A, et al. Diagnostic performance of choline PET for detection of hyperfunctioning parathyroid glands in hyperparathyroidism: a systematic review and meta-analysis. Eur J Nucl Med Mol Imaging 2019;46:751-765. doi: https://doi.org/10.1007/s00259-018-4123-z
Ruda JM, Hollenbeak CS, Stack BC. A systematic review of the diagnosis and treatment of primary hyperparathyroidism from 1995 to 2003. Otolaryngol Head Neck Surg 2005; 132:359-372.
Berri RN, Lloyd LR. Detection of parathyroid adenoma in patients with primary hyperparathyroidism: the use of office-based ultrasound in preoperative localization. Am J Surg 2006; 191:311-314.
Cheung K, Wang TS, Farrokhyar F, Roman SA, Sosa JA. A meta-analysis of preoperative localization techniques for patients with primary hyperparathyroidism. Ann Surg Oncol 2012; 19:577-583.
Vu TH, Guha Thakurta N, Harrell RK, et al. Imaging characteristics of hyperfunctioning parathyroid adenomas using multiphase multidectector computed tomography. J Comput Assist Tomogr 2011; 35:560-567. https://doi.org/10.1097/RCT.0b013e31822a1e70.
Hornung M, Jung EM, Stroszczynski C, Schlitt HJ, Agha A. Contrast-enhanced ultrasonography (CEUS) using early dynamic in microcirculation for localization of pathological parathyroid glands: first-line or complimentary diagnostic modality? Clin Hemorheol Microcirc 2011; 49:83-90. https://doi.org/10.3233/CH-2011-1459.
Parra Ramírez P, Santiago Hernando A, Barquiel Alcalá B, Martín Rojas-Marcos P, Lisbona Catalán A, Álvarez EC. Potential utility of contrast-enhanced ultrasound in the preoperative evaluation of primary hyperparathyroidism. J Ultrasound Med 2019; 38:2565-2571. https://doi.org/10.1002/jum.14949.
Piccin O, D'Alessio P, Cioccoloni E. Pre-operative imaging workup for surgical intervention in primary hyperparathyroidism: a tertiary referral center experience. Am J Otolaryngol 2021; 42:102819. https://doi.org/10.1016/j.amjoto.2020.102819.

Auteurs

Ottavio Piccin (O)

Department of Otolaryngology Head and Neck Surgery, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.

Pasquale D'Alessio (P)

Department of Otolaryngology Head and Neck Surgery, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.

Carla Serra (C)

Department of Organ Insufficiency and Transplantation, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.

Cristina Felicani (C)

Department of Organ Insufficiency and Transplantation, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.

Valentina Vicennati (V)

Department of Endocrinology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.

Andrea Repaci (A)

Department of Endocrinology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.

Uberto Pagotto (U)

Department of Endocrinology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.

Ottavio Cavicchi (O)

Department of Otolaryngology Head and Neck Surgery, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH