Focal Epilepsy in Individuals with Laron Syndrome.
Epilepsy
Insulin-like growth factor-1
Laron syndrome
Seizures
Journal
Hormone research in paediatrics
ISSN: 1663-2826
Titre abrégé: Horm Res Paediatr
Pays: Switzerland
ID NLM: 101525157
Informations de publication
Date de publication:
2022
2022
Historique:
received:
21
10
2021
accepted:
31
01
2022
pubmed:
1
4
2022
medline:
9
8
2022
entrez:
31
3
2022
Statut:
ppublish
Résumé
The aim of the study was to describe focal epilepsy in patients with Laron syndrome (LS). Data were retrieved from medical records of a single-center cohort of 75 patients with LS. We describe for the first time 4 patients with concomitant focal epilepsy and LS. Two of them experienced episodes of status epilepticus. Electroencephalogram examination in all 4 patients showed interictal epileptiform discharges in the temporal regions. Three achieved long-term seizure freedom on antiseizure medications. Patients with LS may be at risk of developing focal epilepsy, which seems to be unrelated to hypoglycemic episodes in childhood.
Identifiants
pubmed: 35358968
pii: 000524350
doi: 10.1159/000524350
pmc: PMC9501736
doi:
Types de publication
News
Langues
eng
Sous-ensembles de citation
IM
Pagination
286-290Informations de copyright
© 2022 The Author(s). Published by S. Karger AG, Basel.
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