Case Report and Review of Literature: Familial Malignant Pleural Mesothelioma in a 39 Years Old Patient With an Inconclusive

BAP1 mutation PET scan familial pleural mesothelioma uniportal VATS

Journal

Frontiers in surgery
ISSN: 2296-875X
Titre abrégé: Front Surg
Pays: Switzerland
ID NLM: 101645127

Informations de publication

Date de publication:
2022
Historique:
received: 21 11 2021
accepted: 10 02 2022
entrez: 1 4 2022
pubmed: 2 4 2022
medline: 2 4 2022
Statut: epublish

Résumé

Malignant pleural mesothelioma (MPM) is a rare yet aggressive neoplasm that was linked only to asbestos exposure for decades, although familial clusters were diagnosed with MPM without a known history of asbestos exposure most likely due to genetic susceptibility. Here, we describe a case of familial malignant mesothelioma in a 39 years old patient with a confirmed BAP1 mutation in addition to a known family history with the same mutation. The patient presented with progressive shortness of breath and recurrent pleural effusions and diagnosis was made through biopsies taken during uniportal Video-Assisted Thoracoscopic Surgery. After the inconclusive result of

Identifiants

pubmed: 35360426
doi: 10.3389/fsurg.2022.819596
pmc: PMC8963911
doi:

Types de publication

Case Reports

Langues

eng

Pagination

819596

Informations de copyright

Copyright © 2022 Idkedek, Tahayneh, Abu-Akar and Bakri.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Mayar Idkedek (M)

Medical Research Club, Faculty of Medicine, Al-Quds University, Jerusalem, Palestine.

Kareem S Tahayneh (KS)

Medical Research Club, Faculty of Medicine, Al-Quds University, Jerusalem, Palestine.

Firas Abu-Akar (F)

Department of Cardiothoracic Surgery, Al-Makassed Charitable Society Hospital, Jerusalem, Palestine.

Izzeddin A Bakri (IA)

Department of Pathology, Al-Makassed Charitable Society Hospital, Jerusalem, Palestine.

Classifications MeSH