A molecular reappraisal of matrix-producing breast metaplastic carcinoma highlighted by PLAG1 and MYC rearrangements.


Journal

Tumori
ISSN: 2038-2529
Titre abrégé: Tumori
Pays: United States
ID NLM: 0111356

Informations de publication

Date de publication:
Apr 2023
Historique:
medline: 4 4 2023
pubmed: 2 4 2022
entrez: 1 4 2022
Statut: ppublish

Résumé

Very little is currently known about molecular alteration of matrix-producing carcinoma of the breast. However, the morphological similarity with other neoplasm with a myxo-chondroid component is remarkable. In this pilot study we evaluated the molecular alterations involving We evaluated Among the 12 cases of matrix producing carcinomas we found that the three cases harboring This is the first report to the best of our knowledge that shows a possible correlation between a matrix producing carcinoma with

Sections du résumé

BACKGROUND UNASSIGNED
Very little is currently known about molecular alteration of matrix-producing carcinoma of the breast. However, the morphological similarity with other neoplasm with a myxo-chondroid component is remarkable. In this pilot study we evaluated the molecular alterations involving
METHODS UNASSIGNED
We evaluated
RESULTS UNASSIGNED
Among the 12 cases of matrix producing carcinomas we found that the three cases harboring
CONCLUSION UNASSIGNED
This is the first report to the best of our knowledge that shows a possible correlation between a matrix producing carcinoma with

Identifiants

pubmed: 35361013
doi: 10.1177/03008916221080190
pmc: PMC10070549
doi:

Substances chimiques

DNA-Binding Proteins 0
PLAG1 protein, human 0
Transcription Factors 0
Proto-Oncogene Proteins c-myc 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

197-202

Références

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Auteurs

Rebecca Salvatori (R)

Department of Surgical Pathology, European Institute of Oncology, IRCCS, Milan, Italy.
University "Statale" of Milan, School of Medicine, Milan, Italy.

Marco Manzoni (M)

Department of Surgical Pathology, European Institute of Oncology, IRCCS, Milan, Italy.

Daniela Lepanto (D)

Department of Surgical Pathology, European Institute of Oncology, IRCCS, Milan, Italy.

Viviana Stufano (V)

Department of Surgical Pathology, European Institute of Oncology, IRCCS, Milan, Italy.

Simona Pessina (S)

Department of Surgical Pathology, European Institute of Oncology, IRCCS, Milan, Italy.

Chiara Zanetti (C)

Department of Surgical Pathology, European Institute of Oncology, IRCCS, Milan, Italy.

Fabio Bassi (F)

Department of Breast Surgery, European Institute of Oncology, IRCCS, Milan, Italy.

Giovanni Mazzarol (G)

Department of Surgical Pathology, European Institute of Oncology, IRCCS, Milan, Italy.

Emilia Montagna (E)

Department of Breast Medical Oncology, European Institute of Oncology, IRCCS, Milan, Italy.

Fausto Maffini (F)

Department of Surgical Pathology, European Institute of Oncology, IRCCS, Milan, Italy.

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Classifications MeSH