Separation anxiety: Splitting PD-L1 from CD80 suppresses autoimmunity.

Antigen-Presenting Cells Anxiety, Separation Autoimmunity B7-1 Antigen B7-H1 Antigen Humans

Journal

Science immunology
ISSN: 2470-9468
Titre abrégé: Sci Immunol
Pays: United States
ID NLM: 101688624

Informations de publication

Date de publication:
04 2022
Historique:
entrez: 1 4 2022
pubmed: 2 4 2022
medline: 6 4 2022
Statut: ppublish

Résumé

A monoclonal antibody targeting CD80 on antigen presenting cells disrupts cis-interactions with PD-L1, reviving T cell inhibitory checkpoint signaling to suppress autoimmunity.

Identifiants

DOI: 10.1126/sciimmunol.abq1728 PMID: 35363545
pubmed: 35363545
doi: 10.1126/sciimmunol.abq1728
doi:

Substances chimiques

B7-1 Antigen 0
B7-H1 Antigen 0

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

eabq1728

Commentaires et corrections

Type : CommentOn

Auteurs

Nathan A Bracey (NA)

Jonathan S Maltzman (JS)

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Cellules présentatrices d'antigène › Separation anxiety: Splitting PD-L1 from CD80...
questionsmedicales.fr › Troubles mentaux › Troubles du développement neurologique › Angoisse de la séparation › Separation anxiety: Splitting PD-L1 from CD80...
questionsmedicales.fr › Phénomènes du système immunitaire › Immunité › Auto-immunité › Separation anxiety: Splitting PD-L1 from CD80...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Antigènes B7 › Antigène CD80 › Separation anxiety: Splitting PD-L1 from CD80...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Antigènes B7 › Antigène CD274 › Separation anxiety: Splitting PD-L1 from CD80...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Separation anxiety: Splitting PD-L1 from CD80...