Very late intubation in COVID-19 patients: a forgotten prognosis factor?

Acute respiratory distress syndrome COVID 19 High flow nasal oxygen therapy Mechanical ventilation Steroid

Journal

Critical care (London, England)
ISSN: 1466-609X
Titre abrégé: Crit Care
Pays: England
ID NLM: 9801902

Informations de publication

Date de publication:
02 04 2022
Historique:
received: 10 01 2022
accepted: 27 03 2022
entrez: 3 4 2022
pubmed: 4 4 2022
medline: 6 4 2022
Statut: epublish

Résumé

Description of all consecutive critically ill COVID 19 patients hospitalized in ICU in University Hospital of Guadeloupe and outcome according to delay between steroid therapy initiation and mechanical ventilation onset. Very late mechanical ventilation defined as intubation after day 7 of dexamethasone therapy was associated with grim prognosis and a high mortality rate of 87%.

Identifiants

pubmed: 35366941
doi: 10.1186/s13054-022-03966-6
pii: 10.1186/s13054-022-03966-6
pmc: PMC8976275
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

89

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2022. The Author(s).

Références

The RECOVERY Collaborative Group. Dexamethasone in hospitalized patients with Covid-19. N Engl J Med. 2021;384(8):693–704.
doi: 10.1056/NEJMoa2021436
Hermine O, Mariette X, Tharaux P-L, Resche-Rigon M, Porcher R, Ravaud P, et al. Effect of tocilizumab vs usual care in adults hospitalized with COVID-19 and moderate or severe pneumonia: a randomized clinical trial. JAMA Intern Med. 2021;181(1):32.
doi: 10.1001/jamainternmed.2020.6820
Vera M, Kattan E, Born P, Rivas E, Amthauer M, Nesvadba A, et al. Intubation timing as determinant of outcome in patients with acute respiratory distress syndrome by SARS-CoV-2 infection. J Crit Care. 2021;65:164–9.
doi: 10.1016/j.jcrc.2021.06.008
Azoulay E, Fartoukh M, Darmon M, Géri G, Voiriot G, Dupont T, et al. Increased mortality in patients with severe SARS-CoV-2 infection admitted within seven days of disease onset. Intensive Care Med. 2020;46(9):1714–22.
doi: 10.1007/s00134-020-06202-3
Battaglini D, Robba C, Ball L, Silva PL, Cruz FF, Pelosi P, et al. Noninvasive respiratory support and patient self-inflicted lung injury in COVID-19: a narrative review. Br J Anaesth. 2021;127(3):353–64.
doi: 10.1016/j.bja.2021.05.024
Karagiannidis C, Hentschker C, Westhoff M, Weber-Carstens S, Janssens U, Kluge S, et al. Observational study of changes in utilization and outcomes in mechanical ventilation in COVID-19. PLOS ONE. 2022;17(1):e0262315.
doi: 10.1371/journal.pone.0262315

Auteurs

Laurent Camous (L)

Intensive Care Unit, Guadeloupe University Hospital, Chemin Chauvel, 97139, Les Abymes,, Guadeloupe, France. laurent.camous@chu-guadeloupe.fr.
Reanimation Médicale et Chirurgicale, Centre Hospitalier Universitaire de Pointe À Pitre, Chemin Chauvel, 97139, Les Abymes, Guadeloupe, France. laurent.camous@chu-guadeloupe.fr.

Jean-David Pommier (JD)

Intensive Care Unit, Guadeloupe University Hospital, Chemin Chauvel, 97139, Les Abymes,, Guadeloupe, France.
Institut Pasteur de la Guadeloupe, Morne Jolivière, 97183, Abymes, France.

Frederic Martino (F)

Intensive Care Unit, Guadeloupe University Hospital, Chemin Chauvel, 97139, Les Abymes,, Guadeloupe, France.
INSERM UMR S_1134, Biologie Intégrée du Globule Rouge, Antilles-Guyane University, 97157, Pointe-à-Pitre, France.

Benoît Tressieres (B)

Antilles-Guyane Clinical Investigation Center, Inserm CIC 1424, Guadeloupe University Hospital, 97139, Les Abymes, Guadeloupe, France.

Alexandre Demoule (A)

AP-HP, Groupe Hospitalier Universitaire APHP-Sorbonne Université, site Pitié-Salpêtrière, Service de Médecine Intensive - Réanimation (Département R3S), Paris, France.
INSERM, UMRS1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Sorbonne Université, 75005, Paris, France.

Marc Valette (M)

Intensive Care Unit, Guadeloupe University Hospital, Chemin Chauvel, 97139, Les Abymes,, Guadeloupe, France.

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