Hormonal Treatment of Acne and Hidradenitis Suppurativa in Adolescent Patients.
Acne
Antiandrogen
Combined oral contraceptive
Hormonal therapy
Spironolactone
Journal
Dermatologic clinics
ISSN: 1558-0520
Titre abrégé: Dermatol Clin
Pays: United States
ID NLM: 8300886
Informations de publication
Date de publication:
Apr 2022
Apr 2022
Historique:
entrez:
3
4
2022
pubmed:
4
4
2022
medline:
6
4
2022
Statut:
ppublish
Résumé
Homeostasis of the cutaneous microenvironment is complex and depends on multiple intrinsic and extrinsic factors, including the influence of hormones. Hormones exert action on the hair follicle and associated sebaceous glands via both endocrine and intracrine mechanisms. The profound impact of hormonal action on follicular homeostasis can be leveraged in the treatment of disorders, such as acne and hidradenitis suppurativa. The clinician must have an intimate knowledge of the rationale for use, mechanism of action, and possible side effects of hormonal therapy when using these agents to treat adolescents with cutaneous disease.
Identifiants
pubmed: 35366970
pii: S0733-8635(21)00094-2
doi: 10.1016/j.det.2021.12.004
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
167-178Informations de copyright
Copyright © 2021 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Disclosures Ryan M. Svoboda, MD and Nanjiba Nawaz, BA have no relevant financial disclosures. Andrea L. Zaenglein, MD: Abbvie (investigator), Arcutis (investigator), Cassiopea (advisory board), Incyte (investigator), Pfizer (investigator, consultant), Regeneron (advisory board), Verrica (advisory board), Pediatric Dermatology (editor-in-chief), UptoDate (author).