Pediatric Acute Liver Failure.

Child Humans Liver Failure, Acute / diagnosis Liver Transplantation / adverse effects Risk Assessment
Acute liver failure Pediatric Transplant

Journal

Critical care clinics
ISSN: 1557-8232
Titre abrégé: Crit Care Clin
Pays: United States
ID NLM: 8507720

Informations de publication

Date de publication:
Apr 2022
Historique:
entrez: 4 4 2022
pubmed: 5 4 2022
medline: 6 4 2022
Statut: ppublish

Résumé

Pediatric acute liver failure is a rare process that results from many different diseases including toxin ingestion and drug overdose, infections, metabolic and genetic disorders, immune-mediated diseases, and ischemia. Up to 50% of children with acute liver failure will never have an underlying cause found. Early identification, supportive care, and disease-directed therapy are critical. For some children liver transplantation is needed for survival, but many children will recover with appropriate therapy, without the need for transplantation. Nonetheless, overall survival is approximately 50% without liver transplantation. Opportunities for improvement in the care of children with acute liver failure still exist.

Identifiants

DOI: 10.1016/j.ccc.2021.11.015 PMID: 35369949
pubmed: 35369949
pii: S0749-0704(21)00103-2
doi: 10.1016/j.ccc.2021.11.015
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

301-315

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure The authors have nothing to disclose.

Auteurs

Catherine Larson-Nath (C)

Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology, and Nutrition, University of Minnesota, 2450 Riverside Avenue, Minneapolis, MN 55454, USA.

Bernadette Vitola (B)

Transplant Institute, Medstar Georgetown University Hospital, 3800 Reservoir Road, NW 2 PHC, Washington, DC 20007, USA. Electronic address: bernadette.vitola@medstar.net.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Pediatric Acute Liver Failure.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Pediatric Acute Liver Failure.
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies du foie › Insuffisance hépatique › Défaillance hépatique › Défaillance hépatique aigüe › Pediatric Acute Liver Failure.
questionsmedicales.fr › Procédures de chirurgie opératoire › Transplantation › Transplantation de tissu › Transplantation hépatique › Pediatric Acute Liver Failure.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Appréciation des risques › Pediatric Acute Liver Failure.