Spatial and Temporal Distribution of Information Processing in the Human Dorsal Anterior Cingulate Cortex.
decision making
electrophysiology
error
human cortex
information theory
Journal
Frontiers in human neuroscience
ISSN: 1662-5161
Titre abrégé: Front Hum Neurosci
Pays: Switzerland
ID NLM: 101477954
Informations de publication
Date de publication:
2022
2022
Historique:
received:
20
09
2021
accepted:
18
02
2022
entrez:
4
4
2022
pubmed:
5
4
2022
medline:
5
4
2022
Statut:
epublish
Résumé
The dorsal anterior cingulate cortex (dACC) is a key node in the human salience network. It has been ascribed motor, pain-processing and affective functions. However, the dynamics of information flow in this complex region and how it responds to inputs remain unclear and are difficult to study using non-invasive electrophysiology. The area is targeted by neurosurgery to treat neuropathic pain. During deep brain stimulation surgery, we recorded local field potentials from this region in humans during a decision-making task requiring motor output. We investigated the spatial and temporal distribution of information flow within the dACC. We demonstrate the existence of a distributed network within the anterior cingulate cortex where discrete nodes demonstrate directed communication following inputs. We show that this network anticipates and responds to the valence of feedback to actions. We further show that these network dynamics adapt following learning. Our results provide evidence for the integration of learning and the response to feedback in a key cognitive region.
Identifiants
pubmed: 35370577
doi: 10.3389/fnhum.2022.780047
pmc: PMC8973009
doi:
Types de publication
Journal Article
Langues
eng
Pagination
780047Subventions
Organisme : British Heart Foundation
ID : PG/19/67/34607
Pays : United Kingdom
Informations de copyright
Copyright © 2022 Keogh, Deli, Zand, Zorman, Boccard-Binet, Parrott, Sigalas, Weiss, Stein, FitzGerald, Aziz, Green and Gillies.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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