Cardiovascular Outcomes in Sleep-Disordered Breathing: Are We Under-estimating?

cardiovascular disease coronary artery disease heart failure nocturnal heart rate changes obstructive sleep apnea positive airway pressure precision medicine sleep-disordered breathing

Journal

Frontiers in neurology
ISSN: 1664-2295
Titre abrégé: Front Neurol
Pays: Switzerland
ID NLM: 101546899

Informations de publication

Date de publication:
2022
Historique:
received: 25 10 2021
accepted: 25 01 2022
entrez: 4 4 2022
pubmed: 5 4 2022
medline: 5 4 2022
Statut: epublish

Résumé

Obstructive sleep apnea is a growing health concern, affecting nearly one billion people worldwide; increasingly recognized as an independent cardiovascular risk factor associated with incident obesity, insulin resistance, hypertension, arrhythmias, stroke, coronary artery disease, and heart failure. The prevalence of obstructive sleep apnea could be underestimated in the previous studies, leading to only modest predictions of cardiovascular outcomes. Using more physiologic data will increase sensitivity for the diagnosis of obstructive sleep apnea. Individuals at high risk of obstructive sleep apnea should be identified so that treatment efforts can be focused on them. This review will assess the evidence for the relationship between obstructive sleep apnea and cardiovascular consequences in the past, present, and future. We will also explore the role of adding physiological data obtained from sleep studies and its ability to enhance the cardiovascular outcome's predictability. Finally, we will discuss future directions and gaps that need further research.

Identifiants

pubmed: 35370882
doi: 10.3389/fneur.2022.801167
pmc: PMC8965583
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

801167

Informations de copyright

Copyright © 2022 Yasir, Pervaiz and Sankari.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Muhammad Yasir (M)

Ascension Providence Hospital, Southfield, MI, United States.
Department of Internal Medicine, Michigan State University, East Lansing, MI, United States.

Amina Pervaiz (A)

Department of Internal Medicine, Wayne State University, Detroit, MI, United States.

Abdulghani Sankari (A)

Department of Internal Medicine, Michigan State University, East Lansing, MI, United States.
Department of Internal Medicine, Wayne State University, Detroit, MI, United States.
Director of Medical Education/Designated Institutional Official (DIO), Ascension Providence Hospital, Southfield, MI, United States.

Classifications MeSH