Review of Studies Comparing Panretinal Photocoagulation and Anti-Vascular Endothelial Growth Factor Therapy in the Treatment of Proliferative Diabetic Retinopathy.

anti vegf diabetes mellitus diabetic retinopathy laser prp pdr

Journal

Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737

Informations de publication

Date de publication:
Feb 2022
Historique:
accepted: 21 02 2022
entrez: 4 4 2022
pubmed: 5 4 2022
medline: 5 4 2022
Statut: epublish

Résumé

Diabetic retinopathy (DR) is among the leading causes of blindness at the global level. A review of studies between 2015 and 2018 found that about 1.7% of the general population with any type of diabetes mellitus suffered from proliferative diabetic retinopathy (PDR). Since the 1960s, panretinal photocoagulation (PRP) has been the mainstay of treatment for PDR. During this period, PRP has been credited with a significant degree of success and a relatively low complication rate. However, the advent of anti-vascular endothelial growth factor (anti-VEGF) therapy with the beginning of the new millennium provided a treatment modality that was noninferior to PRP. A decade-long period of comparisons and debates between these two treatment modalities repeatedly favored anti-VEGF over PRP, as studies demonstrated that the former provided potentially superior outcomes to PRP. The aim of this review is to briefly discuss and compare the relevant studies and evidence supporting these two treatments.

Identifiants

pubmed: 35371631
doi: 10.7759/cureus.22471
pmc: PMC8943265
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

e22471

Informations de copyright

Copyright © 2022, Gunasekaran et al.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

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Auteurs

Thiruvarasu Gunasekaran (T)

Ophthalmology, Hospital Seri Manjung, Sitiawan, MYS.
Ophthalmology, Hospital Bintulu, Bintulu, MYS.

Yuarrani Gunasekaran (Y)

Family Medicine, Klinik Pantai Remis, Perak, MYS.

Pua Tze Hui (P)

Ophthalmology, Hospital Bintulu, Bintulu, MYS.

Classifications MeSH