Facial Diplegia Variant of Guillain-Barré Syndrome in Pregnancy Following COVID-19 Vaccination: A Case Report.

covid-19 covid-19 vaccination facial diplegia guillain-barré syndrome (gbs) neuromuscular

Journal

Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737

Informations de publication

Date de publication:
Feb 2022
Historique:
accepted: 16 02 2022
entrez: 4 4 2022
pubmed: 5 4 2022
medline: 5 4 2022
Statut: epublish

Résumé

Serious neurologic complications from coronavirus disease 2019 (COVID-19) vaccination are rare, and only a few cases of Guillain-Barré syndrome (GBS) have been reported after COVID-19 vaccination. We present the first reported case of the facial diplegia variant of GBS after recent COVID-19 vaccination in a pregnant woman. The 30-year-old patient was 27 weeks pregnant at the time she was diagnosed with the facial diplegia variant of GBS. Her symptoms began two weeks after she received the Ad26.COV2.S COVID-19 vaccine. A thorough evaluation for GBS was done, including a lumbar puncture that demonstrated elevated cerebrospinal fluid (CSF) protein and nerve conduction study (NCS) that found evidence of a diffuse sensorimotor demyelinating polyneuropathy. Nasal swab testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was negative on two occasions five days apart. All other diagnostic testing was unremarkable or nonexplanatory of the patient's clinical presentation. She was started on intravenous immunoglobulin (IVIG) and had significantly improved dysphasia, dysarthria, and facial strength. The patient recovered to baseline four weeks after presentation.

Identifiants

pubmed: 35371813
doi: 10.7759/cureus.22341
pmc: PMC8938242
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e22341

Informations de copyright

Copyright © 2022, Zubair et al.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

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Auteurs

Adeel S Zubair (AS)

Neurology, Yale School of Medicine, New Haven, USA.

Ju Young Bae (JY)

Department of Internal Medicine, Yale New Haven Health Greenwich Hospital, Greenwich, USA.

Kunal Desai (K)

Neurology, Yale School of Medicine, New Haven, USA.

Classifications MeSH