Quantitative analysis of liver function: 3D variable-flip-angle versus Look-Locker T1 relaxometry in hepatocyte-specific contrast-enhanced liver MRI.
Liver
T1 quantification
gadolinium DTPA
magnetic resonance imaging (MRI)
Journal
Quantitative imaging in medicine and surgery
ISSN: 2223-4292
Titre abrégé: Quant Imaging Med Surg
Pays: China
ID NLM: 101577942
Informations de publication
Date de publication:
Apr 2022
Apr 2022
Historique:
received:
03
07
2021
accepted:
12
11
2021
entrez:
4
4
2022
pubmed:
5
4
2022
medline:
5
4
2022
Statut:
ppublish
Résumé
Gd-EOB-DTPA, a liver specific contrast agent with T1- shortening effects, is routinely used in clinical magnetic resonance imaging (MRI) for detection and characterization of focal liver lesions. Gd-EOB-DTPA-enhanced T1 relaxometry has recently received increasing attention as a tool for the quantitative analyses of liver function. However, this T1 relaxometry technique is limited due to various artifacts caused by B1 inhomogeneities and motion artifacts. This study aims to compare two different T1 relaxometry techniques for evaluating liver function as determined using a Ninety-six patients underwent gadoxetic acid-enhanced MRI of the liver at 3T and a T1 relaxometry measurements based on MR sequences, VFA, and LL show a constant change in line with impaired liver function progression. Simple regression models showed a log-linear correlation of Both T1 relaxometry sequences are suitable for the evaluation of liver function based on
Sections du résumé
Background
UNASSIGNED
Gd-EOB-DTPA, a liver specific contrast agent with T1- shortening effects, is routinely used in clinical magnetic resonance imaging (MRI) for detection and characterization of focal liver lesions. Gd-EOB-DTPA-enhanced T1 relaxometry has recently received increasing attention as a tool for the quantitative analyses of liver function. However, this T1 relaxometry technique is limited due to various artifacts caused by B1 inhomogeneities and motion artifacts. This study aims to compare two different T1 relaxometry techniques for evaluating liver function as determined using a
Methods
UNASSIGNED
Ninety-six patients underwent gadoxetic acid-enhanced MRI of the liver at 3T and a
Results
UNASSIGNED
T1 relaxometry measurements based on MR sequences, VFA, and LL show a constant change in line with impaired liver function progression. Simple regression models showed a log-linear correlation of
Conclusions
UNASSIGNED
Both T1 relaxometry sequences are suitable for the evaluation of liver function based on
Identifiants
pubmed: 35371945
doi: 10.21037/qims-21-597
pii: qims-12-04-2509
pmc: PMC8923846
doi:
Types de publication
Journal Article
Langues
eng
Pagination
2509-2522Informations de copyright
2022 Quantitative Imaging in Medicine and Surgery. All rights reserved.
Déclaration de conflit d'intérêts
Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://qims.amegroups.com/article/view/10.21037/qims-21-597/coif). DN is an employee of MR Applications Predevelopment, Siemens Healthineers, Erlangen, Germany. The other authors have no conflicts of interest to declare.
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