New Insights and Challenges Associated With IgA Vasculitis and IgA Vasculitis With Nephritis-Is It Time to Change the Paradigm of the Most Common Systemic Vasculitis in Childhood?
IgA vasculitis
IgA vasculitis nephritis
clinical presentations
diagnostics
disease activity
epidemiology
pathogenesis
treatment
Journal
Frontiers in pediatrics
ISSN: 2296-2360
Titre abrégé: Front Pediatr
Pays: Switzerland
ID NLM: 101615492
Informations de publication
Date de publication:
2022
2022
Historique:
received:
12
01
2022
accepted:
21
02
2022
entrez:
4
4
2022
pubmed:
5
4
2022
medline:
5
4
2022
Statut:
epublish
Résumé
What are the challenges ahead and how have we responded so far when it comes to the non-granulomatous systemic vasculitis, characterized mainly by deposits of IgA immune complexes in the endothelium of small blood vessels-IgA vasculitis (IgAV)? That is the question to which we tried to answer. We summarized existing knowledge about epidemiology, pathogenesis, genetics, diagnostic tests and therapy in this somewhat neglected entity in pediatric rheumatology. Since etiopathogenesis of IgA vasculitis is complex, with factors other than galactose-deficient IgA
Identifiants
pubmed: 35372148
doi: 10.3389/fped.2022.853724
pmc: PMC8965283
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
853724Informations de copyright
Copyright © 2022 Jelusic, Sestan, Giani and Cimaz.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The reviewer DP declared past co-authorships with one of the authors RC and the absence of any ongoing collaboration with any of the authors to the handling editor.
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