Caspase-8 Deficient Osteoblastic Cells Display Alterations in Non-Apoptotic Pathways.
CRISPR/cas9
MC3T3-E1
apoptosis
autophagy
bone
osteogenesis
Journal
Frontiers in cell and developmental biology
ISSN: 2296-634X
Titre abrégé: Front Cell Dev Biol
Pays: Switzerland
ID NLM: 101630250
Informations de publication
Date de publication:
2022
2022
Historique:
received:
14
10
2021
accepted:
28
02
2022
entrez:
4
4
2022
pubmed:
5
4
2022
medline:
5
4
2022
Statut:
epublish
Résumé
Caspase-8 is the key component of the receptor-mediated (extrinsic) apoptotic pathway. Immunological localization of active caspase-8 showed its presence in osteoblasts, including non-apoptotic ones. Further
Identifiants
pubmed: 35372363
doi: 10.3389/fcell.2022.794407
pii: 794407
pmc: PMC8964645
doi:
Types de publication
Journal Article
Langues
eng
Pagination
794407Informations de copyright
Copyright © 2022 Vesela, Killinger, Rihova, Benes, Svandová, Kratochvilová, Trcka, Kleparnik and Matalova.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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