Assessment of the Clinical Diagnosis of Onychomycosis by Dermoscopy.
dermoscopy
diagnosis
fluorescence microscopy
onychomycosis
sensitivity
Journal
Frontiers in surgery
ISSN: 2296-875X
Titre abrégé: Front Surg
Pays: Switzerland
ID NLM: 101645127
Informations de publication
Date de publication:
2022
2022
Historique:
received:
14
01
2022
accepted:
10
02
2022
entrez:
4
4
2022
pubmed:
5
4
2022
medline:
5
4
2022
Statut:
epublish
Résumé
As a common clinical superficial fungal infection, the diagnosis of onychomycosis relies on clinical features, traditional KOH direct microscopy and fungal culture. In recent years, dermoscopy has been widely used in the diagnosis and treatment of infectious diseases and has provided new options for the diagnosis of onychomycosis. To evaluate the value of dermoscopy in the clinical diagnosis of onychomycosis and to explore the relationship between each clinical subtype and the dermoscopic pattern. A retrospective study of 114 cases of clinically suspected onychomycosis was conducted to compare the differences between dermoscopy and fungal pathogenic examination (microscopy and culture) in the diagnostic sensitivity of onychomycosis and to analyze the relationship between nine common dermoscopic modalities and clinical subtypes of onychomycosis. Among the 114 proposed patients, 87 nails with positive fluorescent staining microscopy and/or positive fungal cultures were diagnosed as onychomycosis. The sensitivity and specificity of dermatoscopy, using the mycological findings as a reference, were 86.21 and 33.33%, respectively. The incidence of common dermatoscopic patterns in the 87 nails with confirmed onychomycosis was as follows: white flocculation in 76 cases (87.35%), longitudinal nail pattern in 72 cases (82.76%), jagged changes in the distal nail plate in 69 cases (79.31%) and yellow staining in 46 cases (52.87%), these four patterns were more commonly seen in the distal lateral subungual onychomycosis and total dystrophic onychomycosis, but there was no statistical difference in the positive dermatoscopic pattern between these two types ( Dermoscopy can be an important aid in the diagnosis of onychomycosis, especially when fungal microscopy or culture is not appropriate, but this method is still not a substitute for fungal microscopy and culture.
Sections du résumé
Background
UNASSIGNED
As a common clinical superficial fungal infection, the diagnosis of onychomycosis relies on clinical features, traditional KOH direct microscopy and fungal culture. In recent years, dermoscopy has been widely used in the diagnosis and treatment of infectious diseases and has provided new options for the diagnosis of onychomycosis.
Objective
UNASSIGNED
To evaluate the value of dermoscopy in the clinical diagnosis of onychomycosis and to explore the relationship between each clinical subtype and the dermoscopic pattern.
Methods
UNASSIGNED
A retrospective study of 114 cases of clinically suspected onychomycosis was conducted to compare the differences between dermoscopy and fungal pathogenic examination (microscopy and culture) in the diagnostic sensitivity of onychomycosis and to analyze the relationship between nine common dermoscopic modalities and clinical subtypes of onychomycosis.
Results
UNASSIGNED
Among the 114 proposed patients, 87 nails with positive fluorescent staining microscopy and/or positive fungal cultures were diagnosed as onychomycosis. The sensitivity and specificity of dermatoscopy, using the mycological findings as a reference, were 86.21 and 33.33%, respectively. The incidence of common dermatoscopic patterns in the 87 nails with confirmed onychomycosis was as follows: white flocculation in 76 cases (87.35%), longitudinal nail pattern in 72 cases (82.76%), jagged changes in the distal nail plate in 69 cases (79.31%) and yellow staining in 46 cases (52.87%), these four patterns were more commonly seen in the distal lateral subungual onychomycosis and total dystrophic onychomycosis, but there was no statistical difference in the positive dermatoscopic pattern between these two types (
Conclusion
UNASSIGNED
Dermoscopy can be an important aid in the diagnosis of onychomycosis, especially when fungal microscopy or culture is not appropriate, but this method is still not a substitute for fungal microscopy and culture.
Identifiants
pubmed: 35372459
doi: 10.3389/fsurg.2022.854632
pmc: PMC8966077
doi:
Types de publication
Journal Article
Langues
eng
Pagination
854632Informations de copyright
Copyright © 2022 Ma, Ji, Cen, Qiao, Gao, He and Feng.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Int J Dermatol. 2018 Jul;57(7):837-842
pubmed: 29700806
J Eur Acad Dermatol Venereol. 2013 Apr;27(4):509-13
pubmed: 22040510
Mycoses. 2019 Jan;62(1):32-40
pubmed: 30152879
Arch Dermatol Res. 2020 Apr;312(3):207-212
pubmed: 31728627
J Am Podiatr Med Assoc. 2020 May 1;110(3):
pubmed: 32730601
J Cosmet Dermatol. 2020 May;19(5):1196-1204
pubmed: 31502751
J Eur Acad Dermatol Venereol. 2020 Mar;34(3):580-588
pubmed: 31746067
Postepy Dermatol Alergol. 2018 Jun;35(3):251-258
pubmed: 30008642
Enferm Infecc Microbiol Clin (Engl Ed). 2021 Aug-Sep;39(7):326-329
pubmed: 34353508
Dermatol Pract Concept. 2018 Oct 31;8(4):283-291
pubmed: 30479856
Skin Appendage Disord. 2021 Aug;7(5):351-358
pubmed: 34604322
PLoS One. 2020 Jun 11;15(6):e0234334
pubmed: 32525908
Dermatol Pract Concept. 2015 Apr 30;5(2):39-44
pubmed: 26114050
Br J Dermatol. 2020 Feb;182(2):287-299
pubmed: 31120134
J Am Acad Dermatol. 2019 Apr;80(4):853-867
pubmed: 29959962
Expert Opin Drug Saf. 2020 Nov;19(11):1395-1408
pubmed: 32990062
Indian J Dermatol Venereol Leprol. 2020 Jul-Aug;86(4):341-349
pubmed: 32415047
J Mycol Med. 2020 Jun;30(2):100949
pubmed: 32234349
Int J Dermatol. 2016 Apr;55(4):e172-5
pubmed: 26861859
J Dermatol. 2019 Dec;46(12):1179-1183
pubmed: 31541475
J Dermatol. 2020 May;47(5):e193-e195
pubmed: 32189360
Mycopathologia. 2013 Apr;175(3-4):315-21
pubmed: 23371413
Recent Pat Inflamm Allergy Drug Discov. 2020;14(1):32-45
pubmed: 31738146
Curr Drug Res Rev. 2021;13(1):25-35
pubmed: 32735534
Int J Dermatol. 2018 Feb;57(2):131-138
pubmed: 28653769
Int J Dermatol. 2012 Apr;51(4):483-5
pubmed: 22435443