The Effect of Different Opioids on Acid-Base Balance and Blood Gas Analysis in Hospitalized Dogs.

buprenorphine dog electrolytes glucose lactate methadone tramadol

Journal

Frontiers in veterinary science
ISSN: 2297-1769
Titre abrégé: Front Vet Sci
Pays: Switzerland
ID NLM: 101666658

Informations de publication

Date de publication:
2022
Historique:
received: 26 10 2021
accepted: 17 02 2022
entrez: 4 4 2022
pubmed: 5 4 2022
medline: 5 4 2022
Statut: epublish

Résumé

Pain management is central to veterinary practice, contributing to successful case outcomes and enhancement of the veterinarian-client-patient relationship. Analgesic drugs represent one of the pillars of the multimodal approach to acute and chronic pain management. In dogs, the most used opioids are methadone, buprenorphine and tramadol. Several episodes of hypoglycemia in people treated with tramadol and methadone have recently been described. The aim of this work is to evaluate the changes in the glycemic and acid-base balance induced by tramadol, methadone and buprenorphine in hospitalized dogs. A retrospective review of the medical records of dogs hospitalized for both medical and surgical reasons was performed. During 2018-2020, a total of 876 canine patients were treated with opioids, including 228 with tramadol, 273 with methadone and 375 with buprenorphine. Of all these dogs, only a small percentage met the inclusion criteria presented in the initial design. All the hospitalized animals were monitored daily through clinical examination and blood sampling. Blood samples were obtained before opioid administration (T0), and 24 h (T1) and 48 h (T2) after °pioid administration. The following parameters were evaluated: blood gas value (pH, pCO

Identifiants

pubmed: 35372538
doi: 10.3389/fvets.2022.802186
pmc: PMC8968933
doi:

Types de publication

Journal Article

Langues

eng

Pagination

802186

Informations de copyright

Copyright © 2022 Quintavalla, Spindler, Aldigeri and Fidanzio.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Fausto Quintavalla (F)

Department of Veterinary Sciences, University of Parma, Parma, Italy.

Kevin Pascal Spindler (KP)

Department of Veterinary Sciences, University of Parma, Parma, Italy.

Raffaella Aldigeri (R)

Department of Medicine and Surgery, University of Parma, Parma, Italy.

Francesca Fidanzio (F)

Department of Veterinary Sciences, University of Parma, Parma, Italy.

Classifications MeSH