Assessment of the Concentration of Endogenous Factors Regulating Angiogenesis, VASH-1 and VEGF-A, in the Blood Serum of Patients with Neuroendocrine Neoplasms.


Journal

BioMed research international
ISSN: 2314-6141
Titre abrégé: Biomed Res Int
Pays: United States
ID NLM: 101600173

Informations de publication

Date de publication:
2022
Historique:
received: 16 11 2021
revised: 03 02 2022
accepted: 05 02 2022
entrez: 4 4 2022
pubmed: 5 4 2022
medline: 9 4 2022
Statut: epublish

Résumé

Neuroendocrine neoplasms (NENs) constitute about 2% of all malignant neoplasms, and the angiogenesis process in these tumors is still of a great interest. Vasohibin-1 (VASH-1) is an angiogenesis inhibitor, while vascular endothelial growth factor A (VEGF-A) is one of the main factors promoting vascular formation. The subject of this study was to assess serum concentration of these factors in patients with diagnosed NEN and in control group.

Identifiants

pubmed: 35372578
doi: 10.1155/2022/9084393
pmc: PMC8966743
doi:

Substances chimiques

Angiogenesis Inhibitors 0
Biomarkers 0
Vascular Endothelial Growth Factor A 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

9084393

Informations de copyright

Copyright © 2022 Janusz Strzelczyk et al.

Déclaration de conflit d'intérêts

The authors declare that there is no conflict of interest regarding the publication of this article.

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Auteurs

Janusz Strzelczyk (J)

Department of Endocrinology and Neuroendocrine Tumors, Department of Pathophysiology and Endocrinology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 35 Ceglana St., 40-514 Katowice, Poland.

Monika Wójcik-Giertuga (M)

Department of Endocrinology and Neuroendocrine Tumors, Department of Pathophysiology and Endocrinology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 35 Ceglana St., 40-514 Katowice, Poland.

Piotr Cuber (P)

Natural History Museum, Core Research Laboratories, Molecular Biology, Cromwell Road, London SW7 5BD, UK.

Krzysztof Biernacki (K)

Department of Medical and Molecular Biology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 19 Jordana St., 41-808 Zabrze, Poland.

Beata Kos-Kudła (B)

Department of Endocrinology and Neuroendocrine Tumors, Department of Pathophysiology and Endocrinology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 35 Ceglana St., 40-514 Katowice, Poland.

Joanna Katarzyna Strzelczyk (JK)

Department of Medical and Molecular Biology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 19 Jordana St., 41-808 Zabrze, Poland.

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