Predicting final results of brace treatment of adolescents with idiopathic scoliosis: first out-of-brace radiograph is better than in-brace radiograph-SOSORT 2020 award winner.


Journal

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
ISSN: 1432-0932
Titre abrégé: Eur Spine J
Pays: Germany
ID NLM: 9301980

Informations de publication

Date de publication:
12 2022
Historique:
received: 03 11 2020
accepted: 28 02 2022
revised: 01 02 2022
pubmed: 5 4 2022
medline: 15 12 2022
entrez: 4 4 2022
Statut: ppublish

Résumé

In-brace radiograph of adolescents with idiopathic scoliosis (AIS) has been shown to reflect brace efficacy and the possibility of achieving curve correction. Conversely, the first out-of-brace radiograph could demonstrate the patient's ability to maintain the correction. We aimed to determine which of the two radiographs is the best predictor of the Cobb angle at the end of treatment (final radiograph). Retrospective cohort study of a prospective dataset. The population was selected based on the following inclusion criteria: AIS, age 10-18 years; Risser score 0-2; Cobb angle 25-40°; brace treatment; availability of all radiographs. Pearson correlations provide a first exploration of data. The univariate and multivariate logistic regression model tested the predictors. Finally ROC curve provided a check of model accuracy. A total of 131 patients were included (mean age 13.0 ± 1.3, Cobb angle 33.2 ± 5.5°; 78% females). At the end of treatment, 56% had stabilised, 9% had progressed, and 44% had improved. The difference between the in-brace and final radiographs was 8.0 ± 6.0°, while the difference between the first out-of-brace and final radiographs was 1.8 ± 5.2°. The best predictor of final outcome was the first out-of-brace radiograph (0.80), compared to in-brace (0.68) and baseline (0.59) radiographs. The best cut-offs to predict avoidance of progression were 30% and 10% of the correction rates for the in-brace and first out-of-brace radiographs, respectively. The first out-of-brace radiograph predicts end results better than the in-brace radiograph. It offers an excellent clinical reference for clinicians and patients. The first out-of-brace radiograph should be considered an essential element of future predictive models. LEVEL OF EVIDENCE 1: Diagnostic: individual cross-sectional studies with consistently applied reference standard and blinding.

Identifiants

pubmed: 35376983
doi: 10.1007/s00586-022-07165-3
pii: 10.1007/s00586-022-07165-3
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3519-3526

Commentaires et corrections

Type : ErratumIn

Informations de copyright

© 2022. The Author(s).

Références

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Auteurs

Stefano Negrini (S)

Department of Biomedica, Surgical and Dental Scientes, University "La statale", Milan, Italy.
IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.

Francesca Di Felice (F)

Istituto Scientifico Italiano Colonna Vertebrale (ISICO), Milan, Italy.

Francesco Negrini (F)

Istituti Clinici Scientifici Maugeri IRCCS, Tradate, Varese, Italy.
Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.

Giulia Rebagliati (G)

Istituto Scientifico Italiano Colonna Vertebrale (ISICO), Milan, Italy.

Fabio Zaina (F)

Istituto Scientifico Italiano Colonna Vertebrale (ISICO), Milan, Italy.

Sabrina Donzelli (S)

Istituto Scientifico Italiano Colonna Vertebrale (ISICO), Milan, Italy. sabrina.donzelli@isico.it.

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