Development of a Novel Anti-Mouse CCR2 Monoclonal Antibody (C

Animals Antibodies, Monoclonal CHO Cells Cricetinae Cricetulus Immunization Mice Peptides Rats Receptors, CCR2 / genetics
CCR2 flow cytometry monoclonal antibody

Journal

Monoclonal antibodies in immunodiagnosis and immunotherapy
ISSN: 2167-9436
Titre abrégé: Monoclon Antib Immunodiagn Immunother
Pays: United States
ID NLM: 101590955

Informations de publication

Date de publication:
Apr 2022
Historique:
pubmed: 5 4 2022
medline: 29 4 2022
entrez: 4 4 2022
Statut: ppublish

Résumé

The CC chemokine receptor type-2 (CCR2) belongs to the G-protein-coupled receptor superfamily, expressed on the cell surface of immune cells and tumors. CCR2 binds to the CC motif chemokine 2/monocyte chemoattractant protein-1, a CC chemokine, which is produced by various cells, including immune-related cells and tumors. Therefore, the development of sensitive monoclonal antibodies (mAbs) for CCR2 has been desired for treatment and diagnosis. This study established a novel, specific, and sensitive anti-mouse CCR2 (mCCR2) mAb; C

Identifiants

DOI: 10.1089/mab.2021.0063 PMID: 35377242
pubmed: 35377242
doi: 10.1089/mab.2021.0063
doi:

Substances chimiques

Antibodies, Monoclonal 0
Ccr2 protein, mouse 0
Ccr2 protein, rat 0
Peptides 0
Receptors, CCR2 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

80-86

Auteurs

Tomohiro Tanaka (T)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

Guanjie Li (G)

Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Teizo Asano (T)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

Masaki Saito (M)

Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Mika K Kaneko (MK)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

Hiroyuki Suzuki (H)

Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Yukinari Kato (Y)

Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.
Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.
ORCID: 0000-0001-5385-8201

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Development of a Novel Anti-Mouse CCR2...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Anticorps monoclonaux › Development of a Novel Anti-Mouse CCR2...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules CHO › Development of a Novel Anti-Mouse CCR2...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Arvicolinae › Cricetinae › Development of a Novel Anti-Mouse CCR2...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Arvicolinae › Cricetinae › Cricetulus › Development of a Novel Anti-Mouse CCR2...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pratiques en santé publique › Prévention primaire › Immunisation › Development of a Novel Anti-Mouse CCR2...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Development of a Novel Anti-Mouse CCR2...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Development of a Novel Anti-Mouse CCR2...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Development of a Novel Anti-Mouse CCR2...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs immunologiques › Récepteurs aux cytokines › Récepteurs aux chimiokines › Récepteurs CCR › Récepteurs CCR2 › Development of a Novel Anti-Mouse CCR2...