Regulation of macrophage number and gene transcript levels by activin A and its binding protein, follistatin, in the testes of adult mice.

Activins Animals Carrier Proteins / metabolism Follistatin / genetics Humans Macrophages / metabolism Male Mice Testis
Activin A Follistatin Macrophage function Morphometry Testicular macrophages

Journal

Journal of reproductive immunology
ISSN: 1872-7603
Titre abrégé: J Reprod Immunol
Pays: Ireland
ID NLM: 8001906

Informations de publication

Date de publication:
06 2022
Historique:
received: 06 12 2021
revised: 14 03 2022
accepted: 23 03 2022
pubmed: 5 4 2022
medline: 24 5 2022
entrez: 4 4 2022
Statut: ppublish

Résumé

The cytokine activin A is expressed throughout testicular development and is a critical regulator of macrophage function, but its effects on the testicular macrophages are not well-defined. Macrophage distribution and gene transcript levels were examined in testes of adult mice with reduced levels of either activin A (Inhba

Identifiants

DOI: 10.1016/j.jri.2022.103618 PMID: 35378491
pubmed: 35378491
pii: S0165-0378(22)00147-4
doi: 10.1016/j.jri.2022.103618
pii:
doi:

Substances chimiques

Carrier Proteins 0
Follistatin 0
activin A 0
Activins 104625-48-1

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

103618

Informations de copyright

Copyright © 2022 Elsevier B.V. All rights reserved.

Auteurs

Sneha Biniwale (S)

Centre for Reproductive Health, Hudson Institute of Medical Research, Clayton, Victoria, Australia; Department of Molecular and Translational Sciences, School of Clinical Sciences, Monash University, Clayton, Victoria, Australia; Institute of Anatomy and Cell Biology, Justus-Liebig University Giessen, Giessen, Germany. Electronic address: Sneha.biniwale@monash.edu.

Rukmali Wijayarathna (R)

Centre for Reproductive Health, Hudson Institute of Medical Research, Clayton, Victoria, Australia; Department of Molecular and Translational Sciences, School of Clinical Sciences, Monash University, Clayton, Victoria, Australia.

Christiane Pleuger (C)

Institute of Anatomy and Cell Biology, Justus-Liebig University Giessen, Giessen, Germany; The Hessian Centre of Reproductive Medicine, Justus-Liebig-University, Giessen, Germany.

Sudhanshu Bhushan (S)

Institute of Anatomy and Cell Biology, Justus-Liebig University Giessen, Giessen, Germany; The Hessian Centre of Reproductive Medicine, Justus-Liebig-University, Giessen, Germany.

Kate L Loveland (KL)

Centre for Reproductive Health, Hudson Institute of Medical Research, Clayton, Victoria, Australia; Department of Molecular and Translational Sciences, School of Clinical Sciences, Monash University, Clayton, Victoria, Australia.

Andreas Meinhardt (A)

Centre for Reproductive Health, Hudson Institute of Medical Research, Clayton, Victoria, Australia; Institute of Anatomy and Cell Biology, Justus-Liebig University Giessen, Giessen, Germany; The Hessian Centre of Reproductive Medicine, Justus-Liebig-University, Giessen, Germany.

Mark P Hedger (MP)

Centre for Reproductive Health, Hudson Institute of Medical Research, Clayton, Victoria, Australia; Department of Molecular and Translational Sciences, School of Clinical Sciences, Monash University, Clayton, Victoria, Australia.

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Glycoprotéines › Activines › Regulation of macrophage number and gene...
questionsmedicales.fr › Eucaryotes › Animaux › Regulation of macrophage number and gene...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de transport › Regulation of macrophage number and gene...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de transport › Follistatine › Regulation of macrophage number and gene...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Regulation of macrophage number and gene...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Phagocytes › Macrophages › Regulation of macrophage number and gene...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Regulation of macrophage number and gene...
questionsmedicales.fr › Système endocrine › Glandes endocrines › Gonades › Testicule › Regulation of macrophage number and gene...