Raynaud's phenomenon.
Raynaud’s phenomenon
Systemic sclerosis
assessment
diagnosis
management
Journal
Journal of scleroderma and related disorders
ISSN: 2397-1991
Titre abrégé: J Scleroderma Relat Disord
Pays: England
ID NLM: 101685427
Informations de publication
Date de publication:
Jun 2019
Jun 2019
Historique:
received:
30
09
2018
accepted:
27
11
2018
entrez:
6
4
2022
pubmed:
1
6
2019
medline:
1
6
2019
Statut:
ppublish
Résumé
Raynaud's phenomenon can be either primary (idiopathic) or secondary to underlying disease including systemic sclerosis. Primary Raynaud's phenomenon is very common, affecting approximately 3%-5% of the general population. Although much rarer, systemic sclerosis-related Raynaud's phenomenon can be particularly severe, progressing to digital ulceration in approximately 50% of patients. Raynaud's phenomenon can have a major impact on quality of life. This review has a focus on the systemic sclerosis-related Raynaud's phenomenon (which is the most researched form of Raynaud's phenomenon and probably the most challenging to treat) and on recent advances. Epidemiology (including transition from 'isolated' to systemic sclerosis-related Raynaud's phenomenon), pathogenesis, diagnosis and assessment are discussed, followed by the treatment of both 'uncomplicated' and 'complicated' Raynaud's phenomena (i.e. Raynaud's phenomenon which has progressed to digital ulceration and/or critical ischaemia). Finally, some of the major challenges for the next 5-10 years are highlighted.
Identifiants
pubmed: 35382391
doi: 10.1177/2397198319826467
pii: 10.1177_2397198319826467
pmc: PMC8922643
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
89-101Informations de copyright
© The Author(s) 2019.
Déclaration de conflit d'intérêts
Declaration of conflicting interests: A.L.H. received research funding from Actelion.
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