Genetic variants associated with longitudinal changes in brain structure across the lifespan.


Journal

Nature neuroscience
ISSN: 1546-1726
Titre abrégé: Nat Neurosci
Pays: United States
ID NLM: 9809671

Informations de publication

Date de publication:
04 2022
Historique:
received: 28 08 2020
accepted: 28 02 2022
pubmed: 7 4 2022
medline: 9 4 2022
entrez: 6 4 2022
Statut: ppublish

Résumé

Human brain structure changes throughout the lifespan. Altered brain growth or rates of decline are implicated in a vast range of psychiatric, developmental and neurodegenerative diseases. In this study, we identified common genetic variants that affect rates of brain growth or atrophy in what is, to our knowledge, the first genome-wide association meta-analysis of changes in brain morphology across the lifespan. Longitudinal magnetic resonance imaging data from 15,640 individuals were used to compute rates of change for 15 brain structures. The most robustly identified genes GPR139, DACH1 and APOE are associated with metabolic processes. We demonstrate global genetic overlap with depression, schizophrenia, cognitive functioning, insomnia, height, body mass index and smoking. Gene set findings implicate both early brain development and neurodegenerative processes in the rates of brain changes. Identifying variants involved in structural brain changes may help to determine biological pathways underlying optimal and dysfunctional brain development and aging.

Identifiants

pubmed: 35383335
doi: 10.1038/s41593-022-01042-4
pii: 10.1038/s41593-022-01042-4
pmc: PMC10040206
mid: NIHMS1784902
doi:

Banques de données

ClinicalTrials.gov
['NCT02534363', 'NCT02305832']

Types de publication

Journal Article Meta-Analysis Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

421-432

Subventions

Organisme : NIA NIH HHS
ID : R01 AG058854
Pays : United States
Organisme : Medical Research Council
ID : MR/N027558/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/R024065/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/S020306/1
Pays : United Kingdom
Organisme : NIDA NIH HHS
ID : U01 DA041117
Pays : United States
Organisme : Medical Research Council
ID : MR/N000390/1
Pays : United Kingdom
Organisme : NIBIB NIH HHS
ID : P41 EB015922
Pays : United States
Organisme : Medical Research Council
ID : MC_PC_17228
Pays : United Kingdom
Organisme : NIDA NIH HHS
ID : U24 DA041147
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA051039
Pays : United States
Organisme : Medical Research Council
ID : MR/S003444/1
Pays : United Kingdom
Organisme : NIDA NIH HHS
ID : U01 DA041120
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH120125
Pays : United States
Organisme : NIMH NIH HHS
ID : RC2 MH089995
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA051018
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG064955
Pays : United States
Organisme : NIA NIH HHS
ID : U01 AG068057
Pays : United States
Organisme : MRF
ID : MRF_MRF-058-0004-RG-DESRI
Pays : United Kingdom
Organisme : NIDA NIH HHS
ID : U01 DA041093
Pays : United States
Organisme : Medical Research Council
ID : MR/R00465X/1
Pays : United Kingdom
Organisme : NIA NIH HHS
ID : U01 AG024904
Pays : United States
Organisme : Department of Health
Pays : United Kingdom
Organisme : NIDA NIH HHS
ID : U24 DA041123
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA051038
Pays : United States
Organisme : NIA NIH HHS
ID : P01 AG055367
Pays : United States
Organisme : Medical Research Council
ID : G1001245
Pays : United Kingdom
Organisme : NIDA NIH HHS
ID : U01 DA041134
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH116147
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH085772
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA041022
Pays : United States
Organisme : NIMH NIH HHS
ID : R21 MH107327
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA041156
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA050987
Pays : United States
Organisme : NIBIB NIH HHS
ID : U54 EB020403
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH117601
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA051037
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA051016
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG054002
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA041025
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG060470
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA050989
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA041089
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA050988
Pays : United States
Organisme : NIA NIH HHS
ID : R56 AG058854
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA041106
Pays : United States
Organisme : NIMH NIH HHS
ID : K99 MH116115
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA041028
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA041048
Pays : United States
Organisme : NICHD NIH HHS
ID : R01 HD074051
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA041148
Pays : United States
Organisme : Wellcome Trust
ID : 221890/Z/20/Z
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/M013111/1
Pays : United Kingdom
Organisme : Chief Scientist Office
Pays : United Kingdom
Organisme : NIMH NIH HHS
ID : R01 MH118349
Pays : United States
Organisme : MRF
ID : MRF_C0439
Pays : United Kingdom
Organisme : Medical Research Council
ID : G0701120
Pays : United Kingdom
Organisme : MRF
ID : MRF_MRF-058-0009-RG-DESR-C0759
Pays : United Kingdom
Organisme : NIDA NIH HHS
ID : U01 DA041174
Pays : United States
Organisme : Medical Research Council
ID : MC_QA137853
Pays : United Kingdom
Organisme : NIA NIH HHS
ID : R01 AG022381
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG050595
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG059874
Pays : United States

Investigateurs

Rüdiger Brühl (R)
Dimitri Papadopoulos Orfanos (D)
Tomáš Paus (T)
Sabina Millenet (S)

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer Nature America, Inc.

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Auteurs

Rachel M Brouwer (RM)

Department of Psychiatry, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands. r.m2.brouwer@vu.nl.
Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU Amsterdam, Amsterdam, The Netherlands. r.m2.brouwer@vu.nl.

Marieke Klein (M)

Department of Psychiatry, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands.
Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.
Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands.
Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands.

Katrina L Grasby (KL)

Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.

Hugo G Schnack (HG)

Department of Psychiatry, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands.
Utrecht Institute of Linguistics OTS, Utrecht University, Utrecht, The Netherlands.

Neda Jahanshad (N)

Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA.

Jalmar Teeuw (J)

Department of Psychiatry, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands.

Sophia I Thomopoulos (SI)

Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA.

Emma Sprooten (E)

Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.

Carol E Franz (CE)

Department of Psychiatry and Center for Behavior Genetics of Aging, University of California, San Diego, La Jolla, CA, USA.

Nitin Gogtay (N)

American Psychiatric Association, Washington, DC, USA.

William S Kremen (WS)

Department of Psychiatry and Center for Behavior Genetics of Aging, University of California, San Diego, La Jolla, CA, USA.
VA San Diego Center of Excellence for Stress and Mental Health, San Diego, CA, USA.

Matthew S Panizzon (MS)

Department of Psychiatry and Center for Behavior Genetics of Aging, University of California, San Diego, La Jolla, CA, USA.

Loes M Olde Loohuis (LM)

Center for Neurobehavioral Genetics, University of California, Los Angeles, Los Angeles, CA, USA.

Christopher D Whelan (CD)

Biogen Research and Development, Cambridge, MA, USA.

Moji Aghajani (M)

Department of Psychiatry, Amsterdam Public Health and Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.
Institute of Education & Child Studies, Section Forensic Family & Youth Care, Leiden University, Leiden, The Netherlands.

Clara Alloza (C)

Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón, IiSGM, CIBERSAM, School of Medicine, Universidad Complutense, Madrid, Spain.

Dag Alnæs (D)

NORMENT Centre, University of Oslo, Oslo, Norway.
Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.

Eric Artiges (E)

INSERM U1299 Trajectoires Développementales en Psychiatrie, Ecole Normale Supérieure Paris-Saclay, Université Paris Saclay, Université Paris Cité, CNRS UMR 9010; Centre Borelli, Gif-sur-Yvette, France.

Rosa Ayesa-Arriola (R)

Valdecilla Biomedical Research Institute (IDIVAL), Marqués de Valdecilla University Hospital (HUMV), School of Medicine, University of Cantabria, Santander, Spain.
CIBERSAM, Biomedical Research Network on Mental Health Area, Santander, Spain.
Universidad de Cantabria, Santander, Spain.

Gareth J Barker (GJ)

Department of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.

Mark E Bastin (ME)

Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, UK.
Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Edinburgh Imaging, University of Edinburgh, Edinburgh, UK.

Elisabet Blok (E)

Department of Child and Adolescent Psychiatry/Psychology, Sophia Children's Hospital, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.

Erlend Bøen (E)

Psychosomatic and CL Psychiatry, Oslo University Hospital, Oslo, Norway.

Isabella A Breukelaar (IA)

Brain Dynamics Centre, Westmead Institute for Medical Research, University of Sydney, Westmead, NSW, Australia.

Joanna K Bright (JK)

Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA.

Elizabeth E L Buimer (EEL)

Department of Psychiatry, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands.

Robin Bülow (R)

Institute of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany.

Dara M Cannon (DM)

Centre for Neuroimaging, Cognition and Genomics (NICOG), Clinical Neuroimaging Laboratory, NCBES Galway Neuroscience Centre, College of Medicine Nursing and Health Sciences, National University of Ireland Galway, Galway, Ireland.

Simone Ciufolini (S)

Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

Nicolas A Crossley (NA)

Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Department of Psychiatry, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.

Christienne G Damatac (CG)

Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.

Paola Dazzan (P)

Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

Casper L de Mol (CL)

Department of Neurology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.

Sonja M C de Zwarte (SMC)

Department of Psychiatry, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands.

Sylvane Desrivières (S)

Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.

Covadonga M Díaz-Caneja (CM)

Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón, IiSGM, CIBERSAM, School of Medicine, Universidad Complutense, Madrid, Spain.

Nhat Trung Doan (NT)

NORMENT Centre, University of Oslo, Oslo, Norway.

Katharina Dohm (K)

Institute for Translational Psychiatry, University of Münster, Münster, Germany.

Juliane H Fröhner (JH)

Section of Systems Neuroscience, Department of Psychiatry and Psychotherapy, Technische Universität Dresden, Dresden, Germany.

Janik Goltermann (J)

Institute for Translational Psychiatry, University of Münster, Münster, Germany.

Antoine Grigis (A)

Université Paris-Saclay, CEA, Neurospin, Gif-sur-Yvette, France.

Dominik Grotegerd (D)

Institute for Translational Psychiatry, University of Münster, Münster, Germany.

Laura K M Han (LKM)

Department of Psychiatry, Amsterdam Public Health and Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.

Mathew A Harris (MA)

Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, UK.

Catharina A Hartman (CA)

University of Groningen, University Medical Center Groningen, Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), Groningen, The Netherlands.

Sarah J Heany (SJ)

Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.

Walter Heindel (W)

Clinic for Radiology, University Hospital Münster, Münster, Germany.

Dirk J Heslenfeld (DJ)

Departments of Experimental and Clinical Psychology, Amsterdam, The Netherlands.

Sarah Hohmann (S)

Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany.

Bernd Ittermann (B)

Physikalisch-Technische Bundesanstalt, Berlin, Germany.

Philip R Jansen (PR)

Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU Amsterdam, Amsterdam, The Netherlands.
Department of Child and Adolescent Psychiatry/Psychology, Sophia Children's Hospital, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
Department of Human Genetics, VUmc, Amsterdam UMC, Amsterdam, The Netherlands.

Joost Janssen (J)

Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón, IiSGM, CIBERSAM, School of Medicine, Universidad Complutense, Madrid, Spain.

Tianye Jia (T)

Centre for Population Neuroscience and Precision Medicine (PONS), Institute of Science and Technology for Brain-Inspired Intelligence and MoE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, Fudan University, Shanghai, China.
Centre for Population Neuroscience and Precision Medicine (PONS), Institute of Psychiatry, Psychology and Neuroscience, SGDP Centre, King's College London, London, UK.

Jiyang Jiang (J)

Centre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry and Mental Health, University of New South Wales, Sydney, NSW, Australia.

Christiane Jockwitz (C)

Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany.
Institute for Anatomy I, Medical Faculty & University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany.

Temmuz Karali (T)

Department of Psychiatry and Psychotherapy, University Hospital LMU, Munich, Germany.
NeuroImaging Core Unit Munich (NICUM), University Hospital LMU, Munich, Germany.

Daniel Keeser (D)

Department of Psychiatry and Psychotherapy, University Hospital LMU, Munich, Germany.
NeuroImaging Core Unit Munich (NICUM), University Hospital LMU, Munich, Germany.
Munich Center for Neurosciences (MCN) - Brain & Mind, Planegg-Martinsried, Germany.

Martijn G J C Koevoets (MGJC)

Department of Psychiatry, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands.

Rhoshel K Lenroot (RK)

School of Psychiatry, University of New South Wales, Sydney, NSW, Australia.
School of Psychiatry and Behavioral Sciences, School of Medicine, University of New Mexico, Albuquerque, NM, USA.
Neuroscience Research Australia, Sydney, NSW, Australia.

Berend Malchow (B)

Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany.

René C W Mandl (RCW)

Department of Psychiatry, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands.

Vicente Medel (V)

Department of Psychiatry, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.

Susanne Meinert (S)

Institute for Translational Psychiatry, University of Münster, Münster, Germany.
Institute for Translational Neuroscience, University of Münster, Münster, Germany.

Catherine A Morgan (CA)

School of Psychology and Centre for Brain Research, University of Auckland, Auckland, New Zealand.
Brain Research New Zealand - Rangahau Roro Aotearoa, Auckland, New Zealand.

Thomas W Mühleisen (TW)

Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany.
Cécile and Oskar Vogt Institute for Brain Research, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Department of Biomedicine, University of Basel, Basel, Switzerland.

Leila Nabulsi (L)

Centre for Neuroimaging, Cognition and Genomics (NICOG), Clinical Neuroimaging Laboratory, NCBES Galway Neuroscience Centre, College of Medicine Nursing and Health Sciences, National University of Ireland Galway, Galway, Ireland.

Nils Opel (N)

Institute for Translational Psychiatry, University of Münster, Münster, Germany.
Department of Psychiatry, Jena University Hospital/Friedrich-Schiller-University Jena, Jena, Germany.

Víctor Ortiz-García de la Foz (VO)

Valdecilla Biomedical Research Institute (IDIVAL), Marqués de Valdecilla University Hospital (HUMV), School of Medicine, University of Cantabria, Santander, Spain.
CIBERSAM, Biomedical Research Network on Mental Health Area, Santander, Spain.
Neuroimaging Unit, Technological Facilities, Valdecilla Biomedical Research Institute IDIVAL, Santander, Spain.

Bronwyn J Overs (BJ)

Neuroscience Research Australia, Sydney, NSW, Australia.

Marie-Laure Paillère Martinot (ML)

INSERM U1299 Trajectoires Développementales en Psychiatrie, Ecole Normale Supérieure Paris-Saclay, Université Paris Saclay, Université Paris Cité, CNRS UMR 9010; Centre Borelli, Gif-sur-Yvette, France.
APHP, Sorbonne Université, Pitie-Salpetriere Hospital, Department of Child and Adolescent Psychiatry, Paris, France.

Ronny Redlich (R)

Institute for Translational Psychiatry, University of Münster, Münster, Germany.
Department of Psychology, University of Halle, Halle, Germany.

Tiago Reis Marques (TR)

Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Psychiatric Imaging Group, MRC London Institute of Medical Sciences (LMS), Imperial College London, London, UK.

Jonathan Repple (J)

Institute for Translational Psychiatry, University of Münster, Münster, Germany.

Gloria Roberts (G)

School of Psychiatry, University of New South Wales, Sydney, NSW, Australia.

Gennady V Roshchupkin (GV)

Department of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
Department of Radiology & Nuclear Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Nikita Setiaman (N)

Department of Psychiatry, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands.
Department of Child and Adolescent Psychiatry/Psychology, Sophia Children's Hospital, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.

Elena Shumskaya (E)

Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands.
Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.

Frederike Stein (F)

Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Marburg, Germany.

Gustavo Sudre (G)

Social and Behavioral Research Branch, National Human Genome Research Institute, Bethesda, MD, USA.

Shun Takahashi (S)

Department of Psychiatry and Psychotherapy, University Hospital LMU, Munich, Germany.
Department of Neuropsychiatry, Wakayama Medical University, Wakayama, Japan.

Anbupalam Thalamuthu (A)

Centre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry and Mental Health, University of New South Wales, Sydney, NSW, Australia.

Diana Tordesillas-Gutiérrez (D)

Department of Radiology, IDIVAL, Marqués de Valdecilla University Hospital, Santander, Spain.
Advanced Computing and e-Science, Instituto de Física de Cantabria (UC-CSIC), Santander, Spain.

Aad van der Lugt (A)

Department of Radiology & Nuclear Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Neeltje E M van Haren (NEM)

Department of Psychiatry, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands.
Department of Child and Adolescent Psychiatry/Psychology, Sophia Children's Hospital, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.

Joanna M Wardlaw (JM)

Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, UK.
Centre for Clinical Brain Sciences and UK Dementia Research Institute Centre, University of Edinburgh, Edinburgh, UK.

Wei Wen (W)

Centre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry and Mental Health, University of New South Wales, Sydney, NSW, Australia.

Henk-Jan Westeneng (HJ)

Department of Neurology, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands.

Katharina Wittfeld (K)

German Center for Neurodegenerative Diseases (DZNE), Site Rostock/Greifswald, Greifswald, Germany.
Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.

Alyssa H Zhu (AH)

Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA.

Andre Zugman (A)

Laboratory of Integrative Neuroscience (LiNC), Department of Psychiatry, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.
National Institute of Developmental Psychiatry for Children and Adolescents (INPD), CNPq, São Paulo, Brazil.

Nicola J Armstrong (NJ)

Mathematics and Statistics, Curtin University, Perth, WA, Australia.

Gaia Bonfiglio (G)

Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU Amsterdam, Amsterdam, The Netherlands.

Janita Bralten (J)

Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands.
Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands.

Shareefa Dalvie (S)

Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.

Gail Davies (G)

Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, UK.
Department of Psychology, University of Edinburgh, Edinburgh, UK.

Marta Di Forti (M)

Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.

Linda Ding (L)

Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA.

Gary Donohoe (G)

Centre for Neuroimaging, Cognition and Genomics (NICOG), School of Psychology and Discipline of Biochemistry, National University of Ireland Galway, Galway, Ireland.

Andreas J Forstner (AJ)

Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany.
Centre for Human Genetics, Philipps-University Marburg, Marburg, Germany.
Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany.

Javier Gonzalez-Peñas (J)

Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón, IiSGM, CIBERSAM, School of Medicine, Universidad Complutense, Madrid, Spain.

Joao P O F T Guimaraes (JPOFT)

Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands.
Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.

Georg Homuth (G)

Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.

Jouke-Jan Hottenga (JJ)

Netherlands Twin Register, Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands.

Maria J Knol (MJ)

Department of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.

John B J Kwok (JBJ)

Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia.
School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.

Stephanie Le Hellard (S)

NORMENT Centre of Excellence, Department of Clinical Science, University of Bergen, Bergen, Norway.
Dr. Einar Martens Research Group for Biological Psychiatry, Department of Medical Genetics, Haukeland University Hospital, Bergen, Norway.

Karen A Mather (KA)

Centre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry and Mental Health, University of New South Wales, Sydney, NSW, Australia.
Neuroscience Research Australia, Sydney, NSW, Australia.

Yuri Milaneschi (Y)

Department of Psychiatry, Amsterdam Public Health and Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.

Derek W Morris (DW)

Centre for Neuroimaging, Cognition and Genomics (NICOG), School of Psychology and Discipline of Biochemistry, National University of Ireland Galway, Galway, Ireland.

Markus M Nöthen (MM)

Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany.

Sergi Papiol (S)

CIBERSAM, Biomedical Research Network on Mental Health Area, Santander, Spain.
Department of Psychiatry and Psychotherapy, University Hospital LMU, Munich, Germany.
Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital LMU, Munich, Germany.

Marcella Rietschel (M)

Department of Genetic Epidemiology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

Marcos L Santoro (ML)

Laboratory of Integrative Neuroscience (LiNC), Department of Psychiatry, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.
National Institute of Developmental Psychiatry for Children and Adolescents (INPD), CNPq, São Paulo, Brazil.
Department of Morphology and Genetics, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.

Vidar M Steen (VM)

NORMENT Centre of Excellence, Department of Clinical Science, University of Bergen, Bergen, Norway.
Dr. Einar Martens Research Group for Biological Psychiatry, Department of Medical Genetics, Haukeland University Hospital, Bergen, Norway.

Jason L Stein (JL)

Department of Genetics & UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Fabian Streit (F)

Department of Genetic Epidemiology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

Rick M Tankard (RM)

Mathematics and Statistics, Curtin University, Perth, WA, Australia.

Alexander Teumer (A)

Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.

Dennis van 't Ent (D)

Netherlands Twin Register, Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands.

Dennis van der Meer (D)

NORMENT Centre, University of Oslo, Oslo, Norway.
Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
School of Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.

Kristel R van Eijk (KR)

Department of Neurology, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands.

Evangelos Vassos (E)

Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
NIHR Maudsley Biomedical Research Centre, South London and Maudsley NHS Trust, London, UK.

Javier Vázquez-Bourgon (J)

Valdecilla Biomedical Research Institute (IDIVAL), Marqués de Valdecilla University Hospital (HUMV), School of Medicine, University of Cantabria, Santander, Spain.
CIBERSAM, Biomedical Research Network on Mental Health Area, Santander, Spain.
Universidad de Cantabria, Santander, Spain.

Stephanie H Witt (SH)

Department of Genetic Epidemiology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

Hieab H H Adams (HHH)

Department of Radiology & Nuclear Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Department of Clinical Genetics, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
Latin American Brain Health Institute (BrainLat), Universidad Adolfo Ibanez, Santiago, Chile.

Ingrid Agartz (I)

NORMENT Centre, University of Oslo, Oslo, Norway.
Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Stockholm Region, Stockholm, Sweden.
Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway.

David Ames (D)

Academic Unit for Psychiatry of Old Age, University of Melbourne, Parkville, VIC, Australia.
National Ageing Research Institute, Parkville, VIC, Australia.

Katrin Amunts (K)

Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany.
Cécile and Oskar Vogt Institute for Brain Research, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

Ole A Andreassen (OA)

NORMENT Centre, University of Oslo, Oslo, Norway.
Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.

Celso Arango (C)

Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón, IiSGM, CIBERSAM, School of Medicine, Universidad Complutense, Madrid, Spain.

Tobias Banaschewski (T)

Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany.

Bernhard T Baune (BT)

Department of Psychiatry, University of Melbourne, Melbourne VIC, Australia.
Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, VIC, Australia.
Department of Psychiatry, University of Münster, Münster, Germany.

Sintia I Belangero (SI)

Laboratory of Integrative Neuroscience (LiNC), Department of Psychiatry, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.
National Institute of Developmental Psychiatry for Children and Adolescents (INPD), CNPq, São Paulo, Brazil.
Department of Morphology and Genetics, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.

Arun L W Bokde (ALW)

Discipline of Psychiatry and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland.

Dorret I Boomsma (DI)

Netherlands Twin Register, Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands.

Rodrigo A Bressan (RA)

Laboratory of Integrative Neuroscience (LiNC), Department of Psychiatry, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.
National Institute of Developmental Psychiatry for Children and Adolescents (INPD), CNPq, São Paulo, Brazil.
Instituto Ame Sua Mente, São Paulo, Brazil.

Henry Brodaty (H)

Centre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry and Mental Health, University of New South Wales, Sydney, NSW, Australia.

Jan K Buitelaar (JK)

Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.
Karakter Child and Adolescent Psychiatry University Centre, Nijmegen, The Netherlands.

Wiepke Cahn (W)

Department of Psychiatry, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands.
Altrecht Science, Altrecht Mental Health Institute, Utrecht, The Netherlands.

Svenja Caspers (S)

Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany.
Institute for Anatomy I, Medical Faculty & University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany.

Sven Cichon (S)

Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany.
Department of Biomedicine, University of Basel, Basel, Switzerland.
Institute of Medical Genetics and Pathology, University Hospital Basel, University of Basel, Basel, Switzerland.

Benedicto Crespo-Facorro (B)

CIBERSAM, Biomedical Research Network on Mental Health Area, Santander, Spain.
Department of Psychiatry, Virgen del Rocio University Hospital, School of Medicine, University of Seville, IBIS, Seville, Spain.

Simon R Cox (SR)

Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, UK.
Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration, Edinburgh, UK.

Udo Dannlowski (U)

Institute for Translational Psychiatry, University of Münster, Münster, Germany.

Torbjørn Elvsåshagen (T)

NORMENT Centre, Oslo University Hospital, Oslo, Norway.
Department of Neurology, Oslo University Hospital, Oslo, Norway.
Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

Thomas Espeseth (T)

Department of Psychology, University of Oslo, Oslo, Norway.
Bjørknes College, Oslo, Norway.

Peter G Falkai (PG)

Department of Psychiatry and Psychotherapy, University Hospital LMU, Munich, Germany.

Simon E Fisher (SE)

Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands.
Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands.

Herta Flor (H)

Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

Janice M Fullerton (JM)

Neuroscience Research Australia, Sydney, NSW, Australia.
School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.

Hugh Garavan (H)

Department of Psychiatry, University of Vermont, Burlington, VT, USA.

Penny A Gowland (PA)

Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK.

Hans J Grabe (HJ)

German Center for Neurodegenerative Diseases (DZNE), Site Rostock/Greifswald, Greifswald, Germany.
Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.

Tim Hahn (T)

Institute for Translational Psychiatry, University of Münster, Münster, Germany.

Andreas Heinz (A)

Charité Universitätsmedizin Berlin, Berlin, Germany.

Manon Hillegers (M)

Department of Psychiatry, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands.
Department of Child and Adolescent Psychiatry/Psychology, Sophia Children's Hospital, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.

Jacqueline Hoare (J)

Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.
Faculty of Health, Peninsula Medical School, University of Plymouth, Plymouth, UK.

Pieter J Hoekstra (PJ)

University of Groningen, University Medical Center Groningen, Department of Child and Adolescent Psychiatry & Accare Child Study Center, Groningen, The Netherlands.

Mohammad A Ikram (MA)

Department of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.

Andrea P Jackowski (AP)

Laboratory of Integrative Neuroscience (LiNC), Department of Psychiatry, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.
National Institute of Developmental Psychiatry for Children and Adolescents (INPD), CNPq, São Paulo, Brazil.

Andreas Jansen (A)

Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Marburg, Germany.
Core-Facility Brainimaging, Faculty of Medicine, University of Marburg, Marburg, Germany.

Erik G Jönsson (EG)

NORMENT Centre, University of Oslo, Oslo, Norway.
Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Stockholm Region, Stockholm, Sweden.

Rene S Kahn (RS)

Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
VISN 2 Mental Illness Research, Education & Clinical Center (MIRECC), James J. Peters Department of Veterans Affairs Medical Center, Bronx, NY, USA.

Tilo Kircher (T)

Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Marburg, Germany.

Mayuresh S Korgaonkar (MS)

Brain Dynamics Centre, Westmead Institute for Medical Research, University of Sydney, Westmead, NSW, Australia.
Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia.

Axel Krug (A)

Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Marburg, Germany.
Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.

Herve Lemaitre (H)

Groupe d'Imagerie Neurofonctionnelle, Institut des Maladies Neurodégénératives, CNRS UMR 5293, Université de Bordeaux, Centre Broca Nouvelle-Aquitaine, Bordeaux, France.

Ulrik F Malt (UF)

Unit for Psychosomatic Medicine and C-L Psychiatry, University of Oslo, Oslo, Norway.

Jean-Luc Martinot (JL)

INSERM U1299 Trajectoires Développementales en Psychiatrie, Ecole Normale Supérieure Paris-Saclay, Université Paris Saclay, Université Paris Cité, CNRS UMR 9010; Centre Borelli, Gif-sur-Yvette, France.

Colm McDonald (C)

Centre for Neuroimaging, Cognition and Genomics (NICOG), Clinical Neuroimaging Laboratory, NCBES Galway Neuroscience Centre, College of Medicine Nursing and Health Sciences, National University of Ireland Galway, Galway, Ireland.

Philip B Mitchell (PB)

School of Psychiatry, University of New South Wales, Sydney, NSW, Australia.

Ryan L Muetzel (RL)

Department of Child and Adolescent Psychiatry/Psychology, Sophia Children's Hospital, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.

Robin M Murray (RM)

Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

Frauke Nees (F)

Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany.
Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Institute of Medical Psychology and Medical Sociology, University Medical Center Schleswig-Holstein, Kiel University, Kiel, Germany.

Igor Nenadić (I)

Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Marburg, Germany.

Jaap Oosterlaan (J)

Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Emma Neuroscience Group, Department of Pediatrics, Amsterdam Reproduction & Development, Amsterdam, The Netherlands.
Vrije Universiteit, Clinical Neuropsychology Section, Amsterdam, The Netherlands.

Roel A Ophoff (RA)

Center for Neurobehavioral Genetics, University of California, Los Angeles, Los Angeles, CA, USA.
Department of Psychiatry, Erasmus Medical Center, Erasmus University, Rotterdam, The Netherlands.

Pedro M Pan (PM)

Laboratory of Integrative Neuroscience (LiNC), Department of Psychiatry, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.
National Institute of Developmental Psychiatry for Children and Adolescents (INPD), CNPq, São Paulo, Brazil.

Brenda W J H Penninx (BWJH)

Department of Psychiatry, Amsterdam Public Health and Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.

Luise Poustka (L)

Department of Child and Adolescent Psychiatry, University Medical Center Goettingen, Göttingen, Germany.

Perminder S Sachdev (PS)

Centre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry and Mental Health, University of New South Wales, Sydney, NSW, Australia.
Neuropsychiatric Institute, The Prince of Wales Hospital, Sydney, NSW, Australia.

Giovanni A Salum (GA)

National Institute of Developmental Psychiatry for Children and Adolescents (INPD), CNPq, São Paulo, Brazil.
Department of Psychiatry and Legal Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Section on Negative Affect and Social Processes, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.

Peter R Schofield (PR)

Neuroscience Research Australia, Sydney, NSW, Australia.
School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.

Gunter Schumann (G)

Center for Population Neuroscience and Precision Medicine (PONS), Institute for Science and Technology for Brain-inspired Intelligence (ISTBI), Fudan University, Shanghai, China.
PONS Centre, Department of Psychiatry and Clinical Neuroscience, CCM, Charite University Medicine, Berlin, Germany.

Philip Shaw (P)

Social and Behavioral Research Branch, National Human Genome Research Institute, Bethesda, MD, USA.
National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.

Kang Sim (K)

West Region, Institute of Mental Health, Singapore, Singapore.
Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

Michael N Smolka (MN)

Department of Psychiatry and Neuroimaging Center, Technische Universität Dresden, Dresden, Germany.

Dan J Stein (DJ)

SAMRC Unit on Risk & Resilience in Mental Disorders, Department of Psychiatry & Neuroscience Institute, University of Cape Town, Cape Town, South Africa.

Julian N Trollor (JN)

Centre for Healthy Brain Ageing (CHeBA), Discipline of Psychiatry and Mental Health, University of New South Wales, Sydney, NSW, Australia.
Department of Developmental Disability Neuropsychiatry, Discipline of Psychiatry and Mental Health, University of New South Wales, Sydney, NSW, Australia.

Leonard H van den Berg (LH)

Department of Neurology, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands.

Jan H Veldink (JH)

Department of Neurology, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands.

Henrik Walter (H)

Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute for Health, Berlin, Germany.

Lars T Westlye (LT)

NORMENT Centre, University of Oslo, Oslo, Norway.
Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Department of Psychology, University of Oslo, Oslo, Norway.

Robert Whelan (R)

Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland.

Tonya White (T)

Department of Child and Adolescent Psychiatry/Psychology, Sophia Children's Hospital, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
Department of Radiology & Nuclear Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Margaret J Wright (MJ)

Queensland Brain Institute, University of Queensland, Brisbane, QLD, Australia.
Centre for Advanced Imaging, University of Queensland, Brisbane, QLD, Australia.

Sarah E Medland (SE)

QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.

Barbara Franke (B)

Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands.
Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands.
Department of Psychiatry, Radboud University Medical Center, Nijmegen, The Netherlands.

Paul M Thompson (PM)

Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA.

Hilleke E Hulshoff Pol (HE)

Department of Psychiatry, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands. h.e.hulshoffpol@uu.nl.
Department of Psychology, Utrecht University, Utrecht, The Netherlands. h.e.hulshoffpol@uu.nl.

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