What is the optimal duration for a ROAT? The experience of the French Dermatology and Allergology group (DAG).
allergic contact dermatitis
repeated open application test
skin testing
Journal
Contact dermatitis
ISSN: 1600-0536
Titre abrégé: Contact Dermatitis
Pays: England
ID NLM: 7604950
Informations de publication
Date de publication:
Aug 2022
Aug 2022
Historique:
revised:
22
03
2022
received:
05
10
2021
accepted:
25
03
2022
pubmed:
7
4
2022
medline:
19
7
2022
entrez:
6
4
2022
Statut:
ppublish
Résumé
The repeated open application test (ROAT) is an adjuvant investigation measure to patch testing in the diagnosis of allergic contact dermatitis. ESCD recommends a 15 days duration but its overall duration varies according to publications and patients hardly adhere to prolonged ROAT duration beyond 1 week. The Dermatology and Allergy Group of the French Society of Dermatology performed a prospective study with the aim of determining the best duration for the ROAT. A total of 328 ROAT results were collected for topical products, including cosmetics (60%) and topical medications (31.1%). Fifty-nine (18%) ROATs were positive, and 16 (5%) were doubtful. All the positive ROATs occurred within 10 days, with a median time to positivity of 3 days. According to our results, a minimum duration of 10 days is necessary to achieve a positive ROAT to a topical product.
Sections du résumé
BACKGROUND AND OBJECTIVES
OBJECTIVE
The repeated open application test (ROAT) is an adjuvant investigation measure to patch testing in the diagnosis of allergic contact dermatitis. ESCD recommends a 15 days duration but its overall duration varies according to publications and patients hardly adhere to prolonged ROAT duration beyond 1 week.
MATERIALS AND METHODS
METHODS
The Dermatology and Allergy Group of the French Society of Dermatology performed a prospective study with the aim of determining the best duration for the ROAT.
RESULTS
RESULTS
A total of 328 ROAT results were collected for topical products, including cosmetics (60%) and topical medications (31.1%). Fifty-nine (18%) ROATs were positive, and 16 (5%) were doubtful. All the positive ROATs occurred within 10 days, with a median time to positivity of 3 days.
CONCLUSION
CONCLUSIONS
According to our results, a minimum duration of 10 days is necessary to achieve a positive ROAT to a topical product.
Substances chimiques
Allergens
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
170-175Informations de copyright
© 2022 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Références
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