The fMRI correlates of visuo-spatial abilities: sex differences and gender dysphoria.
Gender dysphoria
Transgender people
V1
V5
Visuospatial abilities
Journal
Brain imaging and behavior
ISSN: 1931-7565
Titre abrégé: Brain Imaging Behav
Pays: United States
ID NLM: 101300405
Informations de publication
Date de publication:
Apr 2022
Apr 2022
Historique:
accepted:
13
01
2022
pubmed:
7
4
2022
medline:
19
4
2022
entrez:
6
4
2022
Statut:
ppublish
Résumé
The contribution of brain regions to visuospatial abilities according to sex differences and gender identity is inconsistently described. One potential explaining factor may be the different tasks employed requiring a variable load of working memory and other cognitive resources. Here we asked to 20 cis and 20 transgender participants to undergo functional Magnetic Resonance Imaging during performance of a judgement line of orientation test that was adapted to explore the basic visuospatial processing while minimizing the working memory load. We show that V1 activation may be viewed as a brain area with enhanced activation in males, regardless of participants' gender identity. On its turn, gender identity exclusively influences the visuospatial processing of extrastriate visual areas (V5) in women with gender dysphoria. They showed enhanced V5 activation and an increased functional connectivity between V5 and V1. Overall our neuroimaging results suggest that the basic visuospatial abilities are associated with different activations pattern of cortical visual areas depending on the sex assigned at birth and gender identity.
Identifiants
pubmed: 35384549
doi: 10.1007/s11682-022-00638-5
pii: 10.1007/s11682-022-00638-5
pmc: PMC9010387
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
955-964Informations de copyright
© 2022. The Author(s).
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