Peritoneal Tuberculosis Mimicking Peritoneal Carcinomatosis on 68 Ga-FAPI-04 and 18 F-FDG PET/CT.
Journal
Clinical nuclear medicine
ISSN: 1536-0229
Titre abrégé: Clin Nucl Med
Pays: United States
ID NLM: 7611109
Informations de publication
Date de publication:
01 Aug 2022
01 Aug 2022
Historique:
pubmed:
7
4
2022
medline:
12
7
2022
entrez:
6
4
2022
Statut:
ppublish
Résumé
We report a case of tuberculosis peritonitis in a 26-year-old woman who presented with abdominal pain, fatigue, and weight loss for the last 4 months. Abdominal US and CT demonstrated intra-abdominal massive ascites, misty mesentery, and diffuse peritoneal thickening. In addition, 3 nodular lesions were detected in the right lung. 18 F-FDG PET/CT showed hypermetabolism in lung nodules, mesenteric area, peritoneal thickening, and ascites. 68 Ga-FAPI-04 (fibroblast activation protein-specific inhibitor) PET/CT imaging was also performed; high uptakes were detected in the same regions of 18 F-FDG PET/CT. Tuberculosis diagnosis was made after histopathological examination of wedge resection of the right lung.
Identifiants
pubmed: 35384886
doi: 10.1097/RLU.0000000000004174
pii: 00003072-202208000-00033
doi:
Substances chimiques
68Ga-FAPI
0
Quinolines
0
Fluorodeoxyglucose F18
0Z5B2CJX4D
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e557-e558Informations de copyright
Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflicts of interest and sources of funding: none declared.
Références
Kratochwil C, Flechsig P, Lindner T, et al. 68 Ga-FAPI PET/CT: tracer uptake in 28 different kinds of cancer. J Nucl Med . 2019;60:801–805.
Chen H, Pang Y, Wu J, et al. Comparison of [ 68 Ga]Ga-DOTA-FAPI-04 and [ 18 F] FDG PET/CT for the diagnosis of primary and metastatic lesions in patients with various types of cancer. Eur J Nucl Med Mol Imaging . 2020;47:1820–1832.
Gundogan C, Komek H, Can C, et al. Comparison of 18 F-FDG PET/CT and 68 Ga-FAPI-04 PET/CT in the staging and restaging of gastric adenocarcinoma. Nucl Med Commun . 2022;43:64–72.
Calais J, Mona CE. Will FAPI PET/CT replace FDG PET/CT in the next decade? Point—an important diagnostic, phenotypic, and biomarker role. AJR Am J Roentgenol . 2021;216:305–306.
Zheng S, Lin R, Chen S, et al. Characterization of the benign lesions with increased 68 Ga-FAPI-04 uptake in PET/CT. Ann Nucl Med . 2021;35:1312–1320.
Can C, Gündoğan C, Güzel Y, et al. 68 Ga-FAPI uptake of thyroiditis in a patient with breast cancer. Clin Nucl Med . 2021;46:683–685.
Hotta M, Benz MR, Allen-Auerbach MS, et al. High 68 Ga-FAPI-46 uptake in a pulmonary necrotizing granuloma in a patient with subcutaneous lipoma. Eur J Nucl Med Mol Imaging . 2022;49:1088–1089.
Gu B, Luo Z, He X, et al. 68 Ga-FAPI and 18 F-FDG PET/CT images in a patient with extrapulmonary tuberculosis mimicking malignant tumor. Clin Nucl Med . 2020;45:865–867.
Zheng J, Lin K, Zheng S, et al. 68 Ga-FAPI and 18 F-PET/CT images in intestinal tuberculosis. Clin Nucl Med . 2022;47:239–240.
Hao B, Wu X, Pang Y, et al. [ 18 F]FDG and [ 68 Ga]Ga-DOTA-FAPI-04 PET/CT in the evaluation of tuberculous lesions. Eur J Nucl Med Mol Imaging . 2021;48:651–652.