Sex and Age Differences in Patient-Reported Acute Stroke Symptoms.
behavior
prehospital delay time
sex diferences
signs and symptoms
stroke
Journal
Frontiers in neurology
ISSN: 1664-2295
Titre abrégé: Front Neurol
Pays: Switzerland
ID NLM: 101546899
Informations de publication
Date de publication:
2022
2022
Historique:
received:
31
12
2021
accepted:
11
02
2022
entrez:
7
4
2022
pubmed:
8
4
2022
medline:
8
4
2022
Statut:
epublish
Résumé
Identification of sex- and age-related differences in the presentation of atypical symptoms at stroke onset may reduce prehospital delay and improve stroke treatment if acknowledged at first contact. To explore sex- and age-related differences in patient-reported typical and atypical symptoms of a stroke. We used data from a cross-sectional survey at two non-comprehensive stroke units in the Capital Region of Denmark. Patient-reported symptoms, stroke knowledge, and behavioral response were analyzed by the Chi-square test or a Fisher's exact test separated by sex. Multivariable logistic regression adjusted for covariates were used to explore sex- and age-related differences according to each patient-reported typical or atypical symptoms. In total, 479 patients with acute stroke were included (median age 74 years [25th to 75th percentile: 64-80], and 40.1% were women). Female sex was associated with higher odds of presenting with atypical symptoms, such as loss of consciousness (OR 2.12 [95% CI 1.08-4.18]) and nausea/vomiting (OR 2.33 [95% CI 1.24-4.37]), and lower odds of presenting with lower extremity paresis (OR 0.59 [95% CI 0.39-0.89). With each year of age, the odds decreased of presenting with sensory changes (OR 0.95 [95% CI 0.94-0.97]) and upper extremity paresis (OR 0.98 [95% CI 0.96-0.99]), whereas odds of presenting with dysphagia (OR 1.06 [95% CI 1.02-1.11]) increased. Patients of female sex and younger age reported on admission more frequently atypical stroke symptoms. Attention should be drawn to this possible atypical first presentation to facilitate correct identification and early stroke revascularization treatment to improve the outcome for both sexes.
Sections du résumé
Background
UNASSIGNED
Identification of sex- and age-related differences in the presentation of atypical symptoms at stroke onset may reduce prehospital delay and improve stroke treatment if acknowledged at first contact.
Aim
UNASSIGNED
To explore sex- and age-related differences in patient-reported typical and atypical symptoms of a stroke.
Methods
UNASSIGNED
We used data from a cross-sectional survey at two non-comprehensive stroke units in the Capital Region of Denmark. Patient-reported symptoms, stroke knowledge, and behavioral response were analyzed by the Chi-square test or a Fisher's exact test separated by sex. Multivariable logistic regression adjusted for covariates were used to explore sex- and age-related differences according to each patient-reported typical or atypical symptoms.
Results
UNASSIGNED
In total, 479 patients with acute stroke were included (median age 74 years [25th to 75th percentile: 64-80], and 40.1% were women). Female sex was associated with higher odds of presenting with atypical symptoms, such as loss of consciousness (OR 2.12 [95% CI 1.08-4.18]) and nausea/vomiting (OR 2.33 [95% CI 1.24-4.37]), and lower odds of presenting with lower extremity paresis (OR 0.59 [95% CI 0.39-0.89). With each year of age, the odds decreased of presenting with sensory changes (OR 0.95 [95% CI 0.94-0.97]) and upper extremity paresis (OR 0.98 [95% CI 0.96-0.99]), whereas odds of presenting with dysphagia (OR 1.06 [95% CI 1.02-1.11]) increased.
Conclusions
UNASSIGNED
Patients of female sex and younger age reported on admission more frequently atypical stroke symptoms. Attention should be drawn to this possible atypical first presentation to facilitate correct identification and early stroke revascularization treatment to improve the outcome for both sexes.
Identifiants
pubmed: 35386418
doi: 10.3389/fneur.2022.846690
pmc: PMC8978710
doi:
Types de publication
Journal Article
Langues
eng
Pagination
846690Informations de copyright
Copyright © 2022 Eddelien, Butt, Christensen, Danielsen and Kruuse.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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