Sex differences and modifiable dementia risk factors synergistically influence memory over the adult lifespan.
Journal
Alzheimer's & dementia (Amsterdam, Netherlands)
ISSN: 2352-8729
Titre abrégé: Alzheimers Dement (Amst)
Pays: United States
ID NLM: 101654604
Informations de publication
Date de publication:
2022
2022
Historique:
received:
27
09
2021
revised:
15
02
2022
accepted:
18
02
2022
entrez:
7
4
2022
pubmed:
8
4
2022
medline:
8
4
2022
Statut:
epublish
Résumé
More women than men develop Alzheimer's disease, yet women perform better and show less decline on episodic memory measures, a contradiction that may be accounted for by modifiable risk factors for dementia. Associations among age, sex, modifiable dementia risk factors, and cognition were measured in a cross-sectional online sample ( Across four tests of associative memory and executive functions, only a Face-Name Association task revealed sex differences in associative memory that varied by age. Men had worse memory than women (the equivalent of performing similar to someone 4 years older) across ages. Men had larger age differences than women (ie, worse memory in older ages) among people with no to one risk factor, but not those with multiple risk factors. Because the relationship between dementia risk factors and age-related memory differences varies between men and women, sex-specific dementia prevention approaches are warranted.
Identifiants
pubmed: 35386471
doi: 10.1002/dad2.12301
pii: DAD212301
pmc: PMC8973898
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e12301Informations de copyright
© 2022 The Authors. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring published by Wiley Periodicals, LLC on behalf of Alzheimer's Association.
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