Interactions of Bacteriophages and Bacteria at the Airway Mucosa: New Insights Into the Pathophysiology of Asthma.
airway mucosa
asthma
bacteria
bacteriophages
tripartite symbiosis
Journal
Frontiers in allergy
ISSN: 2673-6101
Titre abrégé: Front Allergy
Pays: Switzerland
ID NLM: 9918227355906676
Informations de publication
Date de publication:
2020
2020
Historique:
received:
14
10
2020
accepted:
29
12
2020
entrez:
7
4
2022
pubmed:
26
1
2021
medline:
26
1
2021
Statut:
epublish
Résumé
The airway epithelium is the primary site where inhaled and resident microbiota interacts between themselves and the host, potentially playing an important role on allergic asthma development and pathophysiology. With the advent of culture independent molecular techniques and high throughput technologies, the complex composition and diversity of bacterial communities of the airways has been well-documented and the notion of the lungs' sterility definitively rejected. Recent studies indicate that the microbial composition of the asthmatic airways across the spectrum of disease severity, differ significantly compared with healthy individuals. In parallel, a growing body of evidence suggests that bacterial viruses (bacteriophages or simply phages), regulating bacterial populations, are present in almost every niche of the human body and can also interact directly with the eukaryotic cells. The triptych of airway epithelial cells, bacterial symbionts and resident phages should be considered as a functional and interdependent unit with direct implications on the respiratory and overall homeostasis. While the role of epithelial cells in asthma pathophysiology is well-established, the tripartite interactions between epithelial cells, bacteria and phages should be scrutinized, both to better understand asthma as a system disorder and to explore potential interventions.
Identifiants
pubmed: 35386933
doi: 10.3389/falgy.2020.617240
pmc: PMC8974763
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
617240Commentaires et corrections
Type : ErratumIn
Informations de copyright
Copyright © 2021 Tzani-Tzanopoulou, Skliros, Megremis, Xepapadaki, Andreakos, Chanishvili, Flemetakis, Kaltsas, Taka, Lebessi, Doudoulakakis and Papadopoulos.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
PLoS One. 2012;7(4):e35945
pubmed: 22545149
Virulence. 2010 Jul-Aug;1(4):309-13
pubmed: 21178461
J Infect Dis. 2016 Nov 1;214(9):1411-1420
pubmed: 27540112
J Physiol Pharmacol. 2008 Dec;59 Suppl 6:421-32
pubmed: 19218666
Cell Host Microbe. 2015 Nov 11;18(5):549-59
pubmed: 26567508
Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1234-8
pubmed: 19141630
PLoS One. 2011 Feb 22;6(2):e16384
pubmed: 21364979
Sci Rep. 2018 Mar 23;8(1):5091
pubmed: 29572482
Microbiology (Reading). 2011 Jan;157(Pt 1):169-178
pubmed: 20847012
J Mol Med (Berl). 2016 Feb;94(2):219-33
pubmed: 26411873
Clin Transl Med. 2019 May 13;8(1):16
pubmed: 31081530
PLoS Pathog. 2017 Mar 22;13(3):e1006292
pubmed: 28328962
Front Immunol. 2018 Oct 16;9:2252
pubmed: 30459750
Genes (Basel). 2020 May 11;11(5):
pubmed: 32403302
Crit Rev Microbiol. 2018 Mar;44(2):125-142
pubmed: 28539074
Front Microbiol. 2015 Jan 23;6:14
pubmed: 25667584
Pediatr Infect Dis J. 2015 Dec;34(12):1296-301
pubmed: 26262821
Cell Microbiol. 2002 Nov;4(11):759-70
pubmed: 12427098
Proc Am Thorac Soc. 2008 Sep 15;5(7):772-7
pubmed: 18757316
BMC Infect Dis. 2011 Jun 20;11:175
pubmed: 21689403
J Appl Microbiol. 2014 Sep;117(3):627-33
pubmed: 24916438
BMC Ear Nose Throat Disord. 2006 May 10;6:10
pubmed: 16686940
Scand J Infect Dis. 2002;34(1):22-7
pubmed: 11874160
PLoS Pathog. 2005 Sep;1(1):e1
pubmed: 16201010
Allergol Int. 2020 Jul;69(3):437-442
pubmed: 31980373
Cell. 2000 Sep 15;102(6):827-37
pubmed: 11030626
Nat Immunol. 2013 Jul;14(7):654-9
pubmed: 23778792
J Virol. 2013 Oct;87(20):11088-95
pubmed: 23926335
J Bacteriol. 2012 Dec;194(24):6969
pubmed: 23209224
Front Pediatr. 2019 Jun 18;7:246
pubmed: 31275909
Nat Commun. 2017 Dec 4;8(1):1915
pubmed: 29203765
Appl Environ Microbiol. 2011 Sep;77(18):6350-6
pubmed: 21803902
N Engl J Med. 2007 Oct 11;357(15):1487-95
pubmed: 17928596
Am J Respir Crit Care Med. 2008 Dec 15;178(12):1271-81
pubmed: 18787220
BMC Genomics. 2011 Jan 26;12:70
pubmed: 21269504
J Infect Dis. 2005 Sep 15;192(6):1029-38
pubmed: 16107956
Antimicrob Agents Chemother. 2013 Jun;57(6):2743-50
pubmed: 23571534
Plast Reconstr Surg. 2013 Feb;131(2):225-234
pubmed: 23357984
Clin Infect Dis. 2009 Jul 1;49(1):124-31
pubmed: 19480579
Cell. 2012 Mar 16;148(6):1258-70
pubmed: 22424233
Glycoconj J. 2001 Oct;18(10):751-8
pubmed: 12441664
Viruses. 2018 Dec 25;11(1):
pubmed: 30585199
BMC Genomics. 2015 Jul 28;16:549
pubmed: 26215258
J Allergy Clin Immunol. 2017 Mar;139(3):826-834.e13
pubmed: 27576124
Cell Microbiol. 2010 Aug;12(8):1158-73
pubmed: 20331639
J Clin Invest. 2011 Sep;121(9):3657-65
pubmed: 21841308
J Virol. 2017 Jun 9;91(13):
pubmed: 28404851
Nat Rev Drug Discov. 2012 Dec;11(12):958-72
pubmed: 23197041
Am J Respir Crit Care Med. 2013 May 15;187(10):1067-75
pubmed: 23491408
PLoS One. 2012;7(6):e38499
pubmed: 22723863
EMBO Rep. 2019 Jun;20(6):
pubmed: 30952693
J Antimicrob Chemother. 2011 Nov;66(11):2448-54
pubmed: 21816767
Antimicrob Agents Chemother. 2017 Jan 24;61(2):
pubmed: 27919889
Microbiol Spectr. 2019 Jul;7(4):
pubmed: 31373270
J Virol. 2013 Mar;87(6):3237-47
pubmed: 23302893
Allergy. 2011 Apr;66(4):549-55
pubmed: 21087214
Lett Appl Microbiol. 2010 Oct;51(4):363-9
pubmed: 20796209
Pediatr Pulmonol. 2018 Oct;53(10):1340-1345
pubmed: 29943915
PLoS One. 2011;6(10):e26198
pubmed: 22022564
Microbiology (Reading). 2008 Apr;154(Pt 4):1178-1184
pubmed: 18375810
Allergol Int. 2018 Jan;67(1):12-17
pubmed: 28941636
Cell Host Microbe. 2015 May 13;17(5):592-602
pubmed: 25974301
Sci Rep. 2019 Nov 11;9(1):16427
pubmed: 31712565
Nat Microbiol. 2017 Jan 09;2:16251
pubmed: 28067906
mBio. 2017 Nov 21;8(6):
pubmed: 29162715
Bacteriophage. 2015 Apr 18;5(1):e1020260
pubmed: 26442188
Microbiol Mol Biol Rev. 2009 Sep;73(3):389-406, Table of Contents
pubmed: 19721084
PLoS One. 2018 Apr 12;13(4):e0195098
pubmed: 29649269
ISME J. 2016 Oct;10(10):2553-5
pubmed: 27070941
Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):E3152-61
pubmed: 23912186
J Microbiol Methods. 2017 Oct;141:48-54
pubmed: 28780272
Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10771-6
pubmed: 23690590
Cell Host Microbe. 2019 Jun 12;25(6):803-814.e5
pubmed: 31175044
JAMA. 2004 Aug 11;292(6):716-20
pubmed: 15304469
Expert Rev Vaccines. 2018 Jun;17(6):503-512
pubmed: 29863956
Ann Allergy Asthma Immunol. 2019 Mar;122(3):270-275
pubmed: 30552986
J Invest Dermatol. 1982 Oct;79(4):250-3
pubmed: 6182249
Glycobiology. 2007 Jul;17(7):698-712
pubmed: 17392389
J Allergy Clin Immunol. 2019 Nov;144(5):1187-1197
pubmed: 31201890
Curr Allergy Asthma Rep. 2014 Dec;14(12):485
pubmed: 25342392
J Clin Microbiol. 2003 Jun;41(6):2378-84
pubmed: 12791852
J Vis Exp. 2011 May 16;(51):
pubmed: 21633326
PLoS One. 2009 Oct 09;4(10):e7370
pubmed: 19816605
Rev Infect Dis. 1981 Mar-Apr;3(2):212-23
pubmed: 7020041
Curr Opin Pulm Med. 2017 Jan;23(1):41-47
pubmed: 27755161
JCI Insight. 2020 Apr 9;5(7):
pubmed: 32208383
Infect Immun. 1996 Jan;64(1):310-8
pubmed: 8557357
Annu Rev Microbiol. 1994;48:585-617
pubmed: 7826020
Expert Opin Ther Targets. 2016;20(1):19-33
pubmed: 26565427
Adv Exp Med Biol. 2001;491:525-42
pubmed: 14533820
Eur Respir J. 2002 Mar;19(3):546-56
pubmed: 11936537
Microbiome. 2018 Jun 9;6(1):104
pubmed: 29885665
Lancet Respir Med. 2014 Mar;2(3):238-46
pubmed: 24621685
Microbes Infect. 2008 Jan;10(1):3-11
pubmed: 18069032
J Mol Biol. 2006 Jun 2;359(2):496-507
pubmed: 16631788
Environ Sci Technol Lett. 2015;2(4):84-88
pubmed: 26225354
Infect Genet Evol. 2020 Jun;80:104205
pubmed: 31981610
mBio. 2017 Oct 10;8(5):
pubmed: 29018121
Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10475-6
pubmed: 23749871
Front Immunol. 2020 May 15;11:974
pubmed: 32499788
Microbiol Spectr. 2019 Mar;7(2):
pubmed: 30873934
J Leukoc Biol. 2014 Aug;96(2):233-44
pubmed: 24899588
Pharmaceuticals (Basel). 2015 Sep 09;8(3):525-58
pubmed: 26371010
Curr Opin Investig Drugs. 2003 Aug;4(8):953-8
pubmed: 14508879
Cell Host Microbe. 2015 May 13;17(5):704-15
pubmed: 25865368
Virology. 2009 Oct 10;393(1):16-23
pubmed: 19699505
Nat Rev Microbiol. 2008 Mar;6(3):181-6
pubmed: 18157154
PLoS One. 2013 Oct 22;8(10):e77795
pubmed: 24167583
Nat Rev Immunol. 2014 Dec;14(12):827-35
pubmed: 25421702
Ann Am Thorac Soc. 2017 Nov;14(Supplement_5):S326-S331
pubmed: 29161086
Front Immunol. 2020 Feb 11;11:91
pubmed: 32117248
Nat Commun. 2016 Feb 29;7:10859
pubmed: 26924467
J Appl Microbiol. 2005;98(1):7-13
pubmed: 15610412
J Bacteriol. 2006 Jul;188(13):4996-5001
pubmed: 16788209
Semin Immunopathol. 2020 Feb;42(1):75-93
pubmed: 32072252
J Allergy Clin Immunol. 2007 Dec;120(6):1233-44; quiz 1245-6
pubmed: 18073119
FEBS Lett. 2016 Nov;590(21):3721-3738
pubmed: 27637588
Infect Immun. 2001 Mar;69(3):1440-3
pubmed: 11179310
Exp Ther Med. 2017 May;13(5):1813-1819
pubmed: 28565772
BMC Genomics. 2015 Oct 24;16:860
pubmed: 26497500
ISME J. 2012 May;6(5):915-26
pubmed: 22158393
Immunol Rev. 2017 Sep;279(1):106-122
pubmed: 28856733
Microb Pathog. 2020 Nov;148:104447
pubmed: 32805360
Trends Microbiol. 2007 Jul;15(7):297-300
pubmed: 17543527
Mol Microbiol. 2000 Jul;37(1):13-27
pubmed: 10931302
Nat Rev Microbiol. 2018 Jun;16(6):355-367
pubmed: 29599457
Trends Microbiol. 2021 Jun;29(6):528-541
pubmed: 33243546
Asthma Res Pract. 2017 Jan 6;3:1
pubmed: 28078100
PLoS One. 2011 Feb 28;6(2):e17035
pubmed: 21386965
Medicina (Kaunas). 2018 Oct 13;54(5):
pubmed: 30344303
Sci Rep. 2019 Oct 8;9(1):14441
pubmed: 31595018
Mol Microbiol. 1996 Feb;19(4):803-13
pubmed: 8820650
Cell Mol Immunol. 2021 Apr;18(4):889-904
pubmed: 32901128
PLoS One. 2017 Jan 20;12(1):e0170543
pubmed: 28107528
Eur J Clin Microbiol Infect Dis. 2011 Jan;30(1):7-19
pubmed: 20803226
Int J Chron Obstruct Pulmon Dis. 2016 Mar 01;11:445-53
pubmed: 27042037
Microbiology (Reading). 2003 Oct;149(Pt 10):2759-2767
pubmed: 14523109
Mob Genet Elements. 2011 Jul;1(2):155-158
pubmed: 22016866
Am J Respir Crit Care Med. 2012 Sep 15;186(6):536-45
pubmed: 22798321
J Bacteriol. 1999 Jun;181(12):3618-25
pubmed: 10368133
Am J Respir Crit Care Med. 2016 Oct 1;194(7):807-820
pubmed: 27007260
J Immunol. 2014 Aug 1;193(3):1353-63
pubmed: 24973442
J Bacteriol. 2002 Dec;184(24):6893-905
pubmed: 12446640
Blood. 2009 Apr 2;113(14):3333-6
pubmed: 19196661
Nat Commun. 2018 Jan 10;9(1):141
pubmed: 29321519
J Clin Microbiol. 2005 Dec;43(12):6139-43
pubmed: 16333114
Vaccine. 2013 May 1;31(19):2333-42
pubmed: 23523773
Nat Commun. 2019 Nov 1;10(1):5001
pubmed: 31676759
Eur Respir J. 2007 Jan;29(1):179-84
pubmed: 17197483
Heliyon. 2020 Mar 19;6(3):e03483
pubmed: 32215324
Mol Cell. 1999 Oct;4(4):627-32
pubmed: 10549294
Virology. 2014 Nov;468-470:322-329
pubmed: 25232661
Respir Res. 2012 Apr 18;13:35
pubmed: 22513083
Cell. 2006 Feb 24;124(4):715-27
pubmed: 16497583
Indian J Med Res. 2011 Aug;134:149-61
pubmed: 21911966
PLoS Pathog. 2017 Jul 13;13(7):e1006495
pubmed: 28704569
Ann Allergy Asthma Immunol. 2016 May;116(5):394-401
pubmed: 27153739
Am J Respir Crit Care Med. 2011 Oct 15;184(8):957-63
pubmed: 21680950
Am J Respir Crit Care Med. 2012 May 15;185(10):1073-80
pubmed: 22427533
Ann Am Thorac Soc. 2015 Jun;12(6):821-30
pubmed: 25803243
J Immunol. 2013 Nov 1;191(9):4475-87
pubmed: 24141854
Pediatr Infect Dis J. 2004 Jan;23(1 Suppl):S87-97
pubmed: 14730275
Clin Rev Allergy Immunol. 2019 Apr;56(2):219-233
pubmed: 30206782
J Clin Invest. 2019 Mar 11;129(4):1493-1503
pubmed: 30855278
Int J Med Microbiol. 2008 Jul;298(5-6):505-13
pubmed: 18221914
Allergy. 2013 Sep;68(9):1117-25
pubmed: 23915187
Infect Immun. 2000 Jan;68(1):133-40
pubmed: 10603379
Lancet Infect Dis. 2005 Dec;5(12):751-62
pubmed: 16310147
Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5675-9
pubmed: 11960022
J Allergy Clin Immunol. 2014 May;133(5):1301-7, 1307.e1-3
pubmed: 24698319
Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20236-41
pubmed: 24259713
Infect Immun. 2016 Jan 04;84(3):765-74
pubmed: 26729761
Methods Mol Biol. 2018;1838:111-123
pubmed: 30128993
J Clin Microbiol. 2003 Dec;41(12):5718-25
pubmed: 14662966
J Mol Biol. 1972 Feb 14;63(3):335-48
pubmed: 4536897
Am J Hum Genet. 2019 Apr 4;104(4):665-684
pubmed: 30929738
Arch Med Res. 2010 Oct;41(7):530-5
pubmed: 21167392
Eur Respir J. 2016 Mar;47(3):792-800
pubmed: 26647445
J Virol. 1969 Nov;4(5):797-8
pubmed: 5308021
Emerg Infect Dis. 2012 Nov;18(11):1738-45
pubmed: 23092680
J Bacteriol. 2014 Jul;196(14):2670-80
pubmed: 24816604
Allergy Asthma Immunol Res. 2012 Mar;4(2):59-61
pubmed: 22379599
Lancet. 2004 Jun 5;363(9424):1871-2
pubmed: 15183627
Sci Rep. 2016 Sep 09;6:33000
pubmed: 27609086
Nature. 2010 Jul 15;466(7304):334-8
pubmed: 20631792
Epidemiol Infect. 2013 Mar;141(3):631-8
pubmed: 22687602
J Bacteriol. 1990 Sep;172(9):4852-60
pubmed: 2203732
Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):10400-5
pubmed: 27573828
Infect Immun. 2016 Oct 17;84(11):3152-3160
pubmed: 27550933
PLoS One. 2011;6(9):e24418
pubmed: 21931710
FEMS Immunol Med Microbiol. 2011 Oct;63(1):16-24
pubmed: 21631600
J Med Microbiol. 2012 May;61(Pt 5):678-685
pubmed: 22282460
J Allergy Clin Immunol. 2015 Mar;135(3):811-3.e5
pubmed: 25533526
J Allergy Clin Immunol. 2011 Feb;127(2):372-381.e1-3
pubmed: 21194740
J Infect Dis. 1995 Jul;172(1):119-23
pubmed: 7797901
J Infect Dis. 2003 Mar 15;187(6):1000-9
pubmed: 12660947
FEMS Microbiol Rev. 2014 Sep;38(5):916-31
pubmed: 24617569
Clin Exp Allergy. 2018 May;48(5):513-524
pubmed: 29350877
PLoS One. 2010 Jan 05;5(1):e8578
pubmed: 20052417
Commun Integr Biol. 2013 Mar 1;6(2):e22829
pubmed: 23750294
Mediators Inflamm. 2019 Sep 8;2019:3730519
pubmed: 31582898
Front Immunol. 2020 Apr 28;11:761
pubmed: 32411147
Front Pharmacol. 2018 Nov 28;9:1330
pubmed: 30546305
Adv Exp Med Biol. 2014;795:17-29
pubmed: 24162900
J Allergy Clin Immunol. 2005 Aug;116(2):241-9; quiz 250
pubmed: 16083775
Cell Tissue Res. 2017 Mar;367(3):551-569
pubmed: 28190087
J Theor Biol. 2017 Sep 21;429:241-252
pubmed: 28668337
Infect Immun. 2005 Nov;73(11):7569-77
pubmed: 16239560
Nat Rev Dis Primers. 2015 Sep 10;1:15025
pubmed: 27189668
Nature. 2005 Sep 15;437(7057):356-61
pubmed: 16163346
Microbiome. 2016 Jul 07;4(1):37
pubmed: 27388563
Genetics. 2000 Apr;154(4):1439-50
pubmed: 10747043
Microbiome. 2016 Dec 30;4(1):70
pubmed: 28038686
Clin Exp Allergy. 2016 Nov;46(11):1441-1455
pubmed: 27238549
Infect Immun. 2000 Mar;68(3):1557-62
pubmed: 10678974
Cell Host Microbe. 2017 Jul 12;22(1):38-47.e4
pubmed: 28704651
Front Microbiol. 2018 Jul 23;9:1614
pubmed: 30083140
Nature. 2014 Jan 16;505(7483):412-6
pubmed: 24317696
PLoS One. 2013 May 30;8(5):e64285
pubmed: 23737977
Philos Trans R Soc Lond B Biol Sci. 2017 Dec 5;372(1735):
pubmed: 29061896
Infect Immun. 2016 Dec 29;85(1):
pubmed: 27795361
PLoS One. 2014 Jun 23;9(6):e100645
pubmed: 24955983
Chest. 2017 Oct;152(4):771-779
pubmed: 28716644
Am J Respir Crit Care Med. 2019 Nov 1;200(9):1102-1112
pubmed: 31166782
Am J Respir Cell Mol Biol. 2012 Feb;46(2):127-31
pubmed: 21980056
Clin Microbiol Rev. 1997 Jul;10(3):505-20
pubmed: 9227864
Postgrad Med J. 2007 Feb;83(976):100-4
pubmed: 17308212
J Infect Dis. 2000 Apr;181(4):1376-87
pubmed: 10762569
J Infect Dis. 2005 Jul 15;192(2):249-57
pubmed: 15962219
Annu Rev Physiol. 2016;78:481-504
pubmed: 26527186
Mucosal Immunol. 2019 Jul;12(4):843-850
pubmed: 30976087
Appl Environ Microbiol. 2003 Jan;69(1):18-23
pubmed: 12513972
Cell Microbiol. 2007 Mar;9(3):694-707
pubmed: 17054439
Nat Microbiol. 2019 Oct;4(10):1727-1736
pubmed: 31285584
Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13675-80
pubmed: 26483471
J Expo Sci Environ Epidemiol. 2020 Mar;30(2):219-235
pubmed: 31308484
J Clin Invest. 1999 Jul;104(1):123-33
pubmed: 10393706
Curr Opin Microbiol. 2007 Aug;10(4):382-7
pubmed: 17765600
Gut. 2016 Apr;65(4):575-83
pubmed: 26511795
Vaccine. 2011 Jul 18;29(32):5171-7
pubmed: 21621578
J Allergy Clin Immunol. 2017 Apr;139(4):1071-1081
pubmed: 28390574
Nature. 2014 Oct 2;514(7520):59-64
pubmed: 25279917
PLoS One. 2010 Dec 20;5(12):e15678
pubmed: 21187931
J Virol. 1973 Apr;11(4):585-91
pubmed: 4540713
J Immunol. 2016 Jun 15;196(12):4839-47
pubmed: 27260767
J Mol Evol. 1998 Apr;46(4):389-400
pubmed: 9541533
Eur Respir J. 2016 Jun;47(6):1680-6
pubmed: 27076584
J Immunol. 2019 Mar 15;202(6):1845-1858
pubmed: 30745463